CPLM-022181

CPLM 1.0 - Compendium of Protein Lysine Modification

Tag

Content

CPLM ID

CPLM-022181

UniProt Accession

ACOXL_HUMAN; Q9NUZ1; A2RRB7; B7WPB3; B7WPP7; E9PB20; Q53R27; Q53R31; Q53SC6; Q8TCE7

Genbank Protein ID

AC096670; AC023131; AC096591; AC114776; CH471237; BC022268; BC131514; AK001904

Genbank Nucleotide ID

AAY14796.1; AAY14838.1; AAY24074.1; EAW50357.1; AAH22268.1; AAI31515.2; BAA91970.1

Protein Name

Acyl-coenzyme A oxidase-like protein

Protein Synonyms/Alias

Acyl-CoA oxidase-like protein

Gene Name

ACOXL

Gene Synonyms/Alias

Created Date

July 27, 2013

Organism

Homo sapiens (Human)

NCBI Taxa ID

9606

Lysine Modification

Position	Peptide	Type	References
575	EARSRRPKLGAKL**	ubiquitination	[1]

Reference

[1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]

Functional Description

Sequence Annotation

NP_BIND 350 355 FAD (By similarity).

Keyword

Alternative splicing; Complete proteome; FAD; Flavoprotein; Oxidoreductase; Polymorphism; Reference proteome.

Sequence Source

UniProt (SWISSPROT/TrEMBL); GenBank; EMBL

Protein Length

547 AA

Protein Sequence

MRALTVQRVK FAMDLPLLKR AGQDLAEKTK NFVSRSLVIG EVLSMADMAT GVKCGIIYWL 60
FGGAIRNLGS PEHVTKWFQP LQEQKYTGMF AMTERGHGSN ARGIQTEATF DLSAQEFVID 120
TPCENAEKMY IGNAMYGNYA AVFAQLIIDG RSQGPHCFIV PVRDENGSLY PGVTAIDMMY 180
KEGLHGVDNG ILIFDKVRIP RENLLDKFGS VAPDGQYHSP IRNKSARFNA MLAALTPSRL 240
AVAFQAMGAM KLGLTIAIRY SHSRRQFGPK TKEEVKIIEH QTQTLRLMPH LATALALTFV 300
SRYAGALLDE DVFQGKELVN SRSLQALVAG LKAYSTWENI RCLQDCRECT GGMVVGRELL 360
AQYTKQYEEK PLFGLLQNWA ESVGDKLRTS FLAFNMDTVD DLAFLLKAVK FRERVLQRGL 420
VARIYYKVKT KKEDFFHAWN SCLHHVASLS LAHTHRVTLE QFSLAVKSCP DQEDQTLLMK 480
FCLLYGTKLV FQERAWYLEH KYLTPMASTR IRNQLLDLCD SVKDDARRVI STFNIPHTYL 540
HAPIAGISNP RAAWAFYPAP LQPRPREEAR SRRPKLGAKL 580

Gene Ontology

GO:0005777; C:peroxisome; IEA:InterPro.
GO:0003995; F:acyl-CoA dehydrogenase activity; IEA:InterPro.
GO:0003997; F:acyl-CoA oxidase activity; IEA:InterPro.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
GO:0006635; P:fatty acid beta-oxidation; IEA:InterPro.

Interpro

IPR006090; Acyl-CoA_Oxase/DH_1.
IPR006091; Acyl-CoA_Oxase/DH_cen-dom.
IPR012258; Acyl-CoA_oxidase.
IPR002655; Acyl-CoA_oxidase_C.
IPR009075; AcylCo_DH/oxidase_C.
IPR009100; AcylCoA_DH/oxidase.

Pfam

PF01756; ACOX
PF00441; Acyl-CoA_dh_1
PF02770; Acyl-CoA_dh_M

SMART

PROSITE

PRINTS