CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035184
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Aldh1l2 
Protein Synonyms/Alias
  
Gene Name
 Aldh1l2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
43EVYSHLLKEGHRVVGacetylation[1]
57GVFTVPDKDGKADPLacetylation[1]
181LQRSCDVKPNDTVDSacetylation[1]
213VQLIADGKAPRTPQPacetylation[1]
231ATYEGIQKKENAEIPacetylation[1]
299KKPGLVTKNGLVLFGacetylation[1]
310VLFGNDGKALMVRNLacetylation[1]
408EDVYMARKFGDFIQKacetylation[1]
415KFGDFIQKVVRRLRGacetylation[1]
494DRAVAAAKDAFENGEacetylation[1]
760TRVVEEIKKMKIGDPacetylation[1]
763VEEIKKMKIGDPLDRacetylation[1]
785NHKAHLEKLLQYCETacetylation[1]
910VKQSGFGKDLGEEALacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Oxidoreductase; Phosphopantetheine; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 930 AA 
Protein Sequence
MLWRGSQALR HFSTGRVYFK NKLKLALIGQ SLFGQEVYSH LLKEGHRVVG VFTVPDKDGK 60
ADPLELVLWH RCTTEPPIYK TTTTKPKTKT KNYMWCSKIL FGIERLMLGI CLLLIWQPAT 120
FSPLVLSMIE YNVGRTGKDE SDSALEGTLI MGDKKAGFSV FWADDGLDTG PILLQRSCDV 180
KPNDTVDSLY NRFLFPEGIK AMVEAVQLIA DGKAPRTPQP EEGATYEGIQ KKENAEIPWD 240
QPAEVLHNWI RGHDKVPGAW AEIDGQMVTF YGSSLLTSSV PAGEPLDIRG AKKPGLVTKN 300
GLVLFGNDGK ALMVRNLQFE DGKMIPASQY FSSGETSVVE LTAEELKVAE TIKVIWARIL 360
SNVPVIEDST DFFKSGASSM DVARLVEEIR QKCGGLQLQN EDVYMARKFG DFIQKVVRRL 420
RGEDQEAELV VDYVSKEVNE MTVKMPYQCF INGQFVDAED GETYATINPT DGTTLCRVSY 480
ASLADVDRAV AAAKDAFENG EWGRMNARDR GRLMYRLADL MEENQEELAT IEALDSGAVY 540
TLALKTHIGM SVQTFRYFAG WCDKIQEKGL KLTSNMADGN HILLWSPSLS RPTLMCMHLK 600
YAPYPQMSAF TVTKKGPGKD GDYCIHFQVT PLTALKFAEL TVKAGFPKGV INIIPGSGGV 660
AGQRLSQHPD IRKLGFTGST SVGKQIMKSC AVSNLKKVSL ELGGKSPLII FSDCELDKAV 720
RMGMGAVFFN KGENCIAAGR LFVEEAIHDE FVTRVVEEIK KMKIGDPLDR STDHGPQNHK 780
AHLEKLLQYC ETGVKEGATL VYGGRQVQRP GFFMEPTVFT GVEDHMYLAK EESFGPIMVI 840
SKFQNGDIDG VLQRANNTEY GLASGVFTRD ISKAMYVSDR LEAGTVFINT YNKTDVAAPF 900
GGVKQSGFGK DLGEEALNEY LKTKTVTLEY 930 
Gene Ontology
 GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.
 GO:0008168; F:methyltransferase activity; IEA:InterPro.
 GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
 GO:0009058; P:biosynthetic process; IEA:InterPro.
 GO:0032259; P:methylation; IEA:GOC. 
Interpro
 IPR009081; Acyl_carrier_prot-like.
 IPR016161; Ald_DH/histidinol_DH.
 IPR016163; Ald_DH_C.
 IPR016160; Ald_DH_CS.
 IPR016162; Ald_DH_N.
 IPR015590; Aldehyde_DH_dom.
 IPR005793; Formyl_trans_C.
 IPR002376; Formyl_transf_N.
 IPR011034; Formyl_transferase_C-like.
 IPR001555; GART_AS.
 IPR006162; PPantetheine_attach_site. 
Pfam
 PF00171; Aldedh
 PF02911; Formyl_trans_C
 PF00551; Formyl_trans_N
 PF00550; PP-binding 
SMART
  
PROSITE
 PS50075; ACP_DOMAIN
 PS00070; ALDEHYDE_DEHYDR_CYS
 PS00687; ALDEHYDE_DEHYDR_GLU
 PS00373; GART
 PS00012; PHOSPHOPANTETHEINE 
PRINTS