CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-018240
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Nucleolar complex protein 3 homolog 
Protein Synonyms/Alias
 NOC3 protein homolog; Factor for adipocyte differentiation 24; NOC3-like protein; Nucleolar complex-associated protein 3-like protein 
Gene Name
 NOC3L 
Gene Synonyms/Alias
 AD24; C10orf117; FAD24 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
274KDITPSYKIRPLTEAubiquitination[1, 2]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 
Functional Description
 May be required for adipogenesis (By similarity). 
Sequence Annotation
 MOD_RES 787 787 Phosphoserine.  
Keyword
 Coiled coil; Complete proteome; Nucleus; Phosphoprotein; Polymorphism; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 800 AA 
Protein Sequence
MKARRNKKQI PSFRKLIKTS KVKLENKLKN KQFKQQSTLK KYRKEQRKLR QAVKDAVSKK 60
PIPLENPKEK RPGKRIEREE EEEEEALPLD MMDEDDLQLM KDLGQRVSFL TRDLSSSEPV 120
HAKKRKHERI IDKYEKIPRT LQTAPEKELI HLLPIKDKSG IIPQTREKPV TDSNKDEEDQ 180
EEERELEEEI IEDPIQELTI EEHLIERKKK LQEKKMHIAA LASAILSDPE NNIKKLKELR 240
SMLMEQDPDV AVTVRKLVIV SLMELFKDIT PSYKIRPLTE AEKSTKTRKE TQKLREFEEG 300
LVSQYKFYLE NLEQMVKDWK QRKLKKSNVV SLKAYKGLAE VAVKSLCELL VALPHFNFHN 360
NIIVLIVPLM NDMSKLISEM CCEAVKKLFK QDKLGQASLG VIKVISGFVK GRNYEVRPEM 420
LKTFLCLRIK EVEVKKDTED INKPKKFMTF KEKRKSLSRM QRKWKKAEEK LERELREAEA 480
SESTEKKLKL HTETLNIVFV TYFRILKKAQ RSPLLPAVLE GLAKFAHLIN VEFFDDLLVV 540
LHTLIESGDL SYQESLHCVQ TAFHILSGQG DVLNIDPLKF YTHLYKTLFK LHAGATNEGV 600
EIVLQCLDVM LTKRRKQVSQ QRALAFIKRL CTLALHVLPN SSIGILATTR ILMHTFPKTD 660
LLLDSESQGS GVFLPELDEP EYCNAQNTAL WELHALRRHY HPIVQRFAAH LIAGAPSEGS 720
GALKPELSRR SATELFEAYS MAEMTFNPPV ESSNPKIKGK FLQGDSFLNE DLNQLIKRYS 780
SEVATESPLD FTKYLKTSLH 800 
Gene Ontology
 GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
 GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
 GO:0045444; P:fat cell differentiation; IEA:Compara. 
Interpro
 IPR005612; CCAAT-binding_factor.
 IPR011501; NOC3p.
 IPR016903; Nucleolar_cplx-assoc_3. 
Pfam
 PF03914; CBF
 PF07540; NOC3p 
SMART
  
PROSITE
  
PRINTS