CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013738
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Elongation factor Tu 
Protein Synonyms/Alias
 EF-Tu 
Gene Name
 tuf 
Gene Synonyms/Alias
 GK0104 
Created Date
 July 27, 2013 
Organism
 Geobacillus kaustophilus (strain HTA426) 
NCBI Taxa ID
 235909 
Lysine Modification
Position
Peptide
Type
References
10KAKFERTKPHVNIGTacetylation[1]
172GDEVPVIKGSALKALacetylation[1]
177VIKGSALKALEGDPQacetylation[1]
188GDPQWEEKIIELMNAacetylation[1]
209TPQREVDKPFMMPIEacetylation[1]
238RVERGTLKVGDPVEIacetylation[1]
315AQVYVLTKEEGGRHTacetylation[1]
Reference
 [1] Proteomic analysis of acetylation in thermophilic Geobacillus kaustophilus.
 Lee DW, Kim D, Lee YJ, Kim JA, Choi JY, Kang S, Pan JG.
 Proteomics. 2013 Aug;13(15):2278-82. [PMID: 23696451] 
Functional Description
 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity). 
Sequence Annotation
 NP_BIND 19 26 GTP (By similarity).
 NP_BIND 81 85 GTP (By similarity).
 NP_BIND 136 139 GTP (By similarity).  
Keyword
 Complete proteome; Cytoplasm; Elongation factor; GTP-binding; Nucleotide-binding; Protein biosynthesis. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 395 AA 
Protein Sequence
MAKAKFERTK PHVNIGTIGH VDHGKTTLTA AITTVLAKQG KAEAKAYDQI DAAPEERERG 60
ITISTAHVEY ETDARHYAHV DCPGHADYVK NMITGAAQMD GAILVVSAAD GPMPQTREHI 120
LLSRQVGVPY IVVFLNKCDM VDDEELLELV EMEVRDLLSE YDFPGDEVPV IKGSALKALE 180
GDPQWEEKII ELMNAVDEYI PTPQREVDKP FMMPIEDVFS ITGRGTVATG RVERGTLKVG 240
DPVEIIGLSD EPKTTTVTGV EMFRKLLDQA EAGDNIGALL RGVSRDEVER GQVLAKPGSI 300
TPHTKFKAQV YVLTKEEGGR HTPFFSNYRP QFYFRTTDVT GIITLPEGVE MVMPGDNVEM 360
TVELIAPIAI EEGTKFSIRE GGRTVGAGSV SEIIE 395 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005525; F:GTP binding; IEA:HAMAP.
 GO:0003924; F:GTPase activity; IEA:InterPro.
 GO:0003746; F:translation elongation factor activity; IEA:HAMAP.
 GO:0006184; P:GTP catabolic process; IEA:GOC. 
Interpro
 IPR000795; EF_GTP-bd_dom.
 IPR027417; P-loop_NTPase.
 IPR005225; Small_GTP-bd_dom.
 IPR009001; Transl_elong_EF1A/Init_IF2_C.
 IPR004161; Transl_elong_EFTu/EF1A_2.
 IPR004541; Transl_elong_EFTu/EF1A_bac/org.
 IPR004160; Transl_elong_EFTu/EF1A_C.
 IPR009000; Transl_elong_init/rib_B-barrel. 
Pfam
 PF00009; GTP_EFTU
 PF03144; GTP_EFTU_D2
 PF03143; GTP_EFTU_D3 
SMART
  
PROSITE
 PS00301; EFACTOR_GTP 
PRINTS
 PR00315; ELONGATNFCT.