CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-008926
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Retinol dehydrogenase 7 
Protein Synonyms/Alias
 Retinol dehydrogenase type III; RODH III 
Gene Name
 Rdh7 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
241VKEIYGEKFRDSYMKacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
 Acts on retinol bound on cellular retinol-binding protein (CRBP). 
Sequence Annotation
 NP_BIND 33 57 NADP (By similarity).
 ACT_SITE 176 176 Proton acceptor (By similarity).
 BINDING 164 164 Substrate (By similarity).  
Keyword
 Complete proteome; Endoplasmic reticulum; Microsome; NAD; NADP; Oxidoreductase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 317 AA 
Protein Sequence
MWLYLLALVG LWNLLRLFRE RKVVSHLQDK YVFITGCDSG FGNLLARQLD RRGMRVLAAC 60
LTEKGAEQLR SKTSDRLETV ILDVTKTESI VAATQWVKER VGNRGLWGLV NNAGISVPMG 120
PNEWMRKKDF ASVLDVNLLG VIEVTLNMLP LVRKARGRVV NIASTMGRMS LLGGGYCISK 180
YGVEAFSDSL RRELTYFGVK VAIIEPGGFK TNVTNMERLS DNLKKLWDQA TEEVKEIYGE 240
KFRDSYMKAM ESLVNMCSGD LSLVTDCMEH ALTSCHPRTR YSAGWDAKFF YLPMSYLPTF 300
LSDAVIYWGS VKPARAL 317 
Gene Ontology
 GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
 GO:0004745; F:retinol dehydrogenase activity; IEA:EC.
 GO:0042572; P:retinol metabolic process; IEA:UniProtKB-UniPathway. 
Interpro
 IPR002198; DH_sc/Rdtase_SDR.
 IPR002347; Glc/ribitol_DH.
 IPR016040; NAD(P)-bd_dom.
 IPR020904; Sc_DH/Rdtase_CS. 
Pfam
 PF00106; adh_short 
SMART
  
PROSITE
 PS00061; ADH_SHORT 
PRINTS
 PR00081; GDHRDH.
 PR00080; SDRFAMILY.