UniProt Accession

 TM86B_MOUSE; Q497J1 

Genbank Protein ID

 BC100527 

Genbank Nucleotide ID

 AAI00528.1 

Protein Name

 Lysoplasmalogenase 

Protein Synonyms/Alias

 Transmembrane protein 86B 

Gene Name

 Tmem86b 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
5	***MDARKEGLPLET	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Enzyme catalyzing the degradation of lysoplasmalogen. Lysoplasmalogens are formed by the hydrolysis of the abundant membrane glycerophospholipids plasmalogens. May control the respective levels of plasmalogens and lysoplasmalogens in cells and modulate cell membrane properties (By similarity). 

Sequence Annotation

  

Keyword

 Complete proteome; Cytoplasm; Hydrolase; Membrane; Reference proteome; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 226 AA 

Protein Sequence

Gene Ontology

 GO:0044444; C:cytoplasmic part; ISS:UniProtKB.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0016020; C:membrane; ISS:UniProtKB.
 GO:0047408; F:alkenylglycerophosphocholine hydrolase activity; ISS:UniProtKB.
 GO:0047409; F:alkenylglycerophosphoethanolamine hydrolase activity; ISS:UniProtKB.
 GO:0046485; P:ether lipid metabolic process; ISS:UniProtKB. 

Interpro

 IPR012506; YhhN. 

Pfam

 PF07947; YhhN 

SMART

  

PROSITE

  

PRINTS