CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-002390
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Pheromone a factor receptor 
Protein Synonyms/Alias
  
Gene Name
 STE3 
Gene Synonyms/Alias
 YKL178C 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
424ISLGGFSKVTLDYSEubiquitination[1]
432VTLDYSEKLHNSASSubiquitination[1]
453LCYSPASKEENSSSNubiquitination[1]
Reference
 [1] Computational identification of ubiquitylation sites from protein sequences.
 Tung CW, Ho SY.
 BMC Bioinformatics. 2008 Jul 15;9:310. [PMID: 18625080
Functional Description
 Receptor for the peptide pheromone a factor. 
Sequence Annotation
 REGION 300 470 Hydrophilic.  
Keyword
 Complete proteome; G-protein coupled receptor; Membrane; Pheromone response; Receptor; Reference proteome; Transducer; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 470 AA 
Protein Sequence
MSYKSAIIGL CLLAVILLAP PLAWHSHTKN IPAIILITWL LTMNLTCIVD AAIWSDDDFL 60
TRWDGKGWCD IVIKLQVGAN IGISCAVTNI IYNLHTILKA DSVLPDLSSW TKIVKDLVIS 120
LFTPVMVMGF SYLLQVFRYG IARYNGCQNL LSPTWITTVL YTMWMLIWSF VGAVYATLVL 180
FVFYKKRKDV RDILHCTNSG LNLTRFARLL IFCFIIILVM FPFSVYTFVQ DLQQVEGHYT 240
FKNTHSSTIW NTIIKFDPGR PIYNIWLYVL MSYLVFLIFG LGSDALHMYS KFLRSIKLGF 300
VLDMWKRFID KNKEKRVGIL LNKLSSRKES RNPFSTDSEN YISTCTENYS PCVGTPISQA 360
HFYVDYRIPD DPRKSQNKSK KYLFADKETD DILDEIDLKE SRHIPYVTQG QSFDDEISLG 420
GFSKVTLDYS EKLHNSASSN FEGESLCYSP ASKEENSSSN EHSSENTAGP 470 
Gene Ontology
 GO:0005887; C:integral to plasma membrane; IDA:SGD.
 GO:0004933; F:mating-type a-factor pheromone receptor activity; IMP:SGD.
 GO:0000755; P:cytogamy; IMP:SGD.
 GO:0000750; P:pheromone-dependent signal transduction involved in conjugation with cellular fusion; IMP:SGD. 
Interpro
 IPR001499; GPCR_STE3. 
Pfam
 PF02076; STE3 
SMART
  
PROSITE
  
PRINTS
 PR00899; GPCRSTE3.