UniProt Accession

 Q5NCB5_MOUSE; Q5NCB5 

Genbank Protein ID

 AL645849 

Genbank Nucleotide ID

  

Protein Name

 Immunity-related GTPase family M protein 1 

Protein Synonyms/Alias

  

Gene Name

 Irgm1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
41	ERALREGKLLELVYG	ubiquitination	[1]
234	KLRDTLHKDLSNIRC	ubiquitination	[1]
246	IRCCEPLKTLYGTYE	acetylation	[2]
254	TLYGTYEKIVGDKVA	ubiquitination	[1]
259	YEKIVGDKVAVWKQR	ubiquitination	[1]
264	GDKVAVWKQRIANES	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 288 AA 

Protein Sequence

Gene Ontology

 GO:0005783; C:endoplasmic reticulum; TAS:MGI.
 GO:0016020; C:membrane; IEA:InterPro.
 GO:0005525; F:GTP binding; IEA:InterPro.
 GO:0016817; F:hydrolase activity, acting on acid anhydrides; IEA:InterPro.
 GO:0006952; P:defense response; IMP:MGI. 

Interpro

 IPR007743; Interferon-induced_GTPase.
 IPR027417; P-loop_NTPase. 

Pfam

 PF05049; IIGP 

SMART

  

PROSITE

  

PRINTS