| Tag | Content |
|---|
| CPLM ID | CPLM-015660 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | von Willebrand factor A domain-containing protein 5A |
Protein Synonyms/Alias | Loss of heterozygosity 11 chromosomal region 2 gene A protein homolog; Mast cell surface antigen 1; Masa-1 |
Gene Name | Vwa5a |
Gene Synonyms/Alias | Loh11cr2a; Masa1 |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 12 | WGLITGNKEKVPLKS | acetylation | [1] | | 72 | EALVDGKKIVAELQD | acetylation | [1] | | 80 | IVAELQDKTKAHSKY | acetylation | [1] | | 519 | SRGAVCLKHTLQGKS | acetylation | [1] | | 597 | AINKELNKPVQGPLA | acetylation | [1] |
|
Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | May play a role in tumorigenesis as a tumor suppressor. Altered expression of this protein and disruption of the molecular pathway it is involved in may contribute directly to or modify tumorigenesis (By similarity). |
Sequence Annotation | DOMAIN 1 131 VIT.
DOMAIN 281 469 VWFA. |
Keyword | Complete proteome; Reference proteome; Tumor suppressor. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 822 AA |
Protein Sequence | MEHHWGLITG NKEKVPLKSI SVTLSINDFV AAVAATLHYE NEEKVPIEAM FVFPMDEDSA 60
VYSFEALVDG KKIVAELQDK TKAHSKYEEA LSQGHQAYLL EEDDYSRDVF SCNVGNLQPG 120
TKVAVTLRYV QELPLESDGA LRYLLPAVLN PRYQLSEQSA SSCLNVQKPI VPLEALPYTL 180
SMVATITSQH GIERVQSNCS LSPIQYLTDD KTSAQVSLTE GHKFDRDVEL LIYYREVHSP 240
SVAVEKGMQD KKRDSLMGAP CAMVSFYPDI PEVNASKVCG EFVFLMDRSG SMQTPMRTEE 300
NSQLRIEAAK ETLLLLLKSL PMGCYFNIYG FGSSYEQFFP ESVKYTQETI EEAVERVKRL 360
DADLGGTEIL TPLRNIYKTS SIPGHPLQLF VFTDGEVSDT YSVIREVKLN SKKHRCFSFG 420
IGQGASTSLI KNIARVSGGT AEFITGKDRM QAKALGSLKL ALQCALDDIS LSWELPPGLS 480
VNMLSPEQPT IFRGQRLIIY AQLTGPMPQA ESRGAVCLKH TLQGKSLENK VAFSLQPKEN 540
ANFTIHRLAA KFLIQTKDLG SHEVSKEEKK DVMNISLQSG VLSSFTAFVA INKELNKPVQ 600
GPLAHRVIPR PMIATSTSMF MRSCSRLTGP FKNSRLKRRL CAADYVPYGH ESTVYSSMPS 660
PAPIENQGVA DSSNEKSNSQ NEHKAFGENV VLQLIFLQNA NGSWKLDENL TKILGTTLED 720
TKAANPSQHG DPSAWATILA VLWLHANGQD LKCEWELLER KAVAWLHDHA GRGTTPPPFP 780
SFHLHPREPC LYVLQRTQES LWLSQLCCLR TLSLQLILHF QD 822 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |