| Tag | Content |
|---|
| CPLM ID | CPLM-011604 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Nicotinamide riboside transporter 1 |
Protein Synonyms/Alias | Thiamine transport protein 71 |
Gene Name | NRT1 |
Gene Synonyms/Alias | THI71; YOR071C; YOR29-22 |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 588 | VHQKDDEKHSFSTTQ | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | High-affinity pH-dependent nicotinamide riboside transporter which also transports thiamine with low affinity. Involved in 5-fluorocytosine sensitivity. |
Sequence Annotation | MOD_RES 560 560 Phosphoserine.
MOD_RES 572 572 Phosphoserine. |
Keyword | Cell membrane; Complete proteome; Membrane; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 598 AA |
Protein Sequence | MSFSSIVSKF LRYLEIPAKN RTAVNFLRNP DLQPIKSANQ TWGFWSNLAY WGAVSFTAGT 60
WMSGSAALSV GLSYPETIVS FLLGNVLTII FTMANSYPGY DWKIGFTLAQ RFVFGIYGSA 120
FGIIIRILMS IVNYGSNAWL GGLSINMILD SWSHHYLHLP NTLSPSVAMT TKQLVGFIIF 180
HVLTALCYFM KPYHMNYLLI WSCVATCFAM LGIVIYLTKN AHGVGELFTS TKSTVTGSKR 240
AWAWVYMISY WFGSISPGST NQSDYSRFGS SNLAIWTGSV CALLIPATLV PIFGVISAST 300
CDKLYGKQFW MPMDIFDYWL TNNYSAGARA GAFFCGLCFT MSQMSSTISN CGFATGMDMA 360
GLLPKYVDIK RGALFCACIS WACLPWNFYN SSSTFLTVMS SFGVVMTPII AVMICDNFLI 420
RKRQYSITNA FILKGEYYFT KGVNWRAIVA WVCGMAPGLP GIAWEVNNNY FHDSGIVKFF 480
YGDSFFSFLI SFFVYWGLCV FFPFKITVRH DDKDYYGAFT DEEARKKGMI PYSEISEEEI 540
RAYTLGECYT TGHEYKPESS DNESPELIKT SSENTNVFEI VHQKDDEKHS FSTTQQVV 598 |
Gene Ontology | GO:0016021; C:integral to membrane; ISM:SGD. GO:0005886; C:plasma membrane; ISS:SGD. GO:0034257; F:nicotinamide riboside transmembrane transporter activity; IMP:SGD. GO:0015205; F:nucleobase transmembrane transporter activity; IEA:InterPro. GO:0015888; P:thiamine transport; IGI:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |