Tag | Content |
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CPLM ID | CPLM-024095 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | V-type proton ATPase subunit C 1 |
Protein Synonyms/Alias | V-ATPase subunit C 1; Vacuolar proton pump subunit C 1 |
Gene Name | Atp6v1c1 |
Gene Synonyms/Alias | Atp6c; Atp6c1; Vatc |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
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28 | KLHAATTKNNNLAVS | ubiquitination | [1] | 86 | VLEDSKDKVQENLLA | ubiquitination | [1] | 115 | DMAKYPIKQSLKNIS | ubiquitination | [1] | 127 | NISEIIAKGVTQIDN | ubiquitination | [1] | 137 | TQIDNDLKSRASAYN | ubiquitination | [1] | 147 | ASAYNNLKGNLQNLE | ubiquitination | [1] | 156 | NLQNLERKNAGSLLT | ubiquitination | [1] | 240 | AVDDFRHKARENKFI | ubiquitination | [1] | 259 | QYNEEEMKADKEEMT | ubiquitination | [1] | 262 | EEEMKADKEEMTRLS | ubiquitination | [1] |
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Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. |
Sequence Annotation | MOD_RES 2 2 N-acetylthreonine (By similarity). |
Keyword | Acetylation; Complete proteome; Direct protein sequencing; Hydrogen ion transport; Ion transport; Reference proteome; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 382 AA |
Protein Sequence | MTEFWLISAP GEKTCQQTWE KLHAATTKNN NLAVSSKFNI PDLKVGTLDV LVGLSDELAK 60 LDAFVEGVVK KVAQYMADVL EDSKDKVQEN LLASGVDLVT YITRFQWDMA KYPIKQSLKN 120 ISEIIAKGVT QIDNDLKSRA SAYNNLKGNL QNLERKNAGS LLTRSLAEIV KKDDFVLDSE 180 YLVTLLVVVP KLNHNDWIKQ YETLAEMVVP RSSNVLSEDQ DSYLCNVTLF RKAVDDFRHK 240 ARENKFIVRD FQYNEEEMKA DKEEMTRLST DKKKQFGPLV RWLKVNFSEA FIAWIHIKAL 300 RVFVESVLRY GLPVNFQAML LQPNKKSVKK LREVLHELYK HLDSSAAAII DAPMDIPGLN 360 LSQQEYYPYV YYKIDCNLLE FK 382 |
Gene Ontology | GO:0045177; C:apical part of cell; IEA:Compara. GO:0031410; C:cytoplasmic vesicle; IEA:Compara. GO:0005886; C:plasma membrane; IDA:UniProtKB. GO:0033180; C:proton-transporting V-type ATPase, V1 domain; IEA:InterPro. GO:0008553; F:hydrogen-exporting ATPase activity, phosphorylative mechanism; IDA:MGI. GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro. |
Interpro | |
Pfam | |
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PROSITE | |
PRINTS | |