CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043088
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Nuclear receptor ROR-alpha 
Protein Synonyms/Alias
  
Gene Name
 RORA 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
146GMSRDAVKFGRMSKKubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; DNA-binding; Metal-binding; Nucleus; Reference proteome; Transcription; Transcription regulation; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 153 AA 
Protein Sequence
MRVTVAPQTK PVFSTNELAH LSPPSAPASQ RESGVGLRAS CPTEWGQKVV RGAFRGALRA 60
EKRPAATAQI EIIPCKICGD KSSGIHYGVI TCEGCKGFFR RSQQSNATYS CPRQKNCLID 120
RTSRNRCQHC RLQKCLAVGM SRDAVKFGRM SKK 153 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-KW.
 GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
 GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0043401; P:steroid hormone mediated signaling pathway; IEA:GOC.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR008946; Nucl_hormone_rcpt_ligand-bd.
 IPR001628; Znf_hrmn_rcpt. 
Pfam
 PF00105; zf-C4 
SMART
 SM00399; ZnF_C4 
PROSITE
 PS00031; NUCLEAR_REC_DBD_1
 PS51030; NUCLEAR_REC_DBD_2 
PRINTS
 PR00047; STROIDFINGER.