CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031663
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 GATA zinc finger domain containing 2A, isoform CRA_a 
Protein Synonyms/Alias
 Transcriptional repressor p66-alpha 
Gene Name
 GATAD2A 
Gene Synonyms/Alias
 hCG_2000637 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
135TSTEALMKSSPEEREubiquitination[1]
178QKEATAQKPTGSVGSubiquitination[1]
204TQNIPAGKPSLQTSSubiquitination[2]
233GGQQASSKLGPQASSubiquitination[2]
422PYMCAQCKTDFTCRWubiquitination[2]
452TNQKKALKVEHTSRLubiquitination[2]
465RLKAAFVKALQQEQEubiquitination[2, 3]
488GTAPAQAKAEPTAAPubiquitination[2]
500AAPHPVLKQVIKPRRubiquitination[1, 2]
551HTFSPSPKLQNSASAubiquitination[2]
577ERTVSAGKGSATSNWubiquitination[2]
Reference
 [1] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 634 AA 
Protein Sequence
MTEEACRTRS QKRALERDPT EDDVESKKIK MERGLLASDL NTDGDMRVTP EPGAGPTQGL 60
LRATEATAMA MGRGEGLVGD GPVDMRTSHS DMKSERRPPS PDVIVLSDNE QPSSPRVNGL 120
TTVALKETST EALMKSSPEE RERMIKQLKE ELRLEEAKLV LLKKLRQSQI QKEATAQKPT 180
GSVGSTVTTP PPLVRGTQNI PAGKPSLQTS SARMPGSVIP PPLVRGGQQA SSKLGPQASS 240
QVVMPPLVRG AQQIHSIRQH SSTGPPPLLL APRASVPSVQ IQGQRIIQQG LIRVANVPNT 300
SLLVNIPQPT PASLKGTTAT SAQANSTPTS VASVVTSAES PASRQAAAKL ALRKQLEKTL 360
LEIPPPKPPA PEMNFLPSAA NNEFIYLVGL EEVVQNLLET QAGRMSAATV LSREPYMCAQ 420
CKTDFTCRWR EEKSGAIMCE NCMTTNQKKA LKVEHTSRLK AAFVKALQQE QEIEQRLLQQ 480
GTAPAQAKAE PTAAPHPVLK QVIKPRRKLA FRSGEARDWS NGAVLQASSQ LSRGSATTPR 540
GVLHTFSPSP KLQNSASATA LVSRTGRHSE RTVSAGKGSA TSNWKKTPLS TGGTLAFVSP 600
SLAVHKSSSA VDRQREYLLD MIPPRSIPQS ATWK 634 
Gene Ontology
 GO:0005634; C:nucleus; IDA:HPA.
 GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR000679; Znf_GATA.
 IPR013088; Znf_NHR/GATA. 
Pfam
 PF00320; GATA 
SMART
  
PROSITE
 PS00344; GATA_ZN_FINGER_1
 PS50114; GATA_ZN_FINGER_2 
PRINTS