CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034970
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Cullin 4B (Predicted) 
Protein Synonyms/Alias
 Protein Cul4b 
Gene Name
 Cul4b 
Gene Synonyms/Alias
 Cul4b_predicted; rCG_53225 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
628IAKYVDSKLRAGNKEacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 971 AA 
Protein Sequence
MSRSTKSRER RENDANSEDN SSETSNQERR RCLQGPPRPP YPPLLPPVFP PPTPPPQVRR 60
TRGLQDLGAM KSVCPGTSGF SSPNPSAASA AAQEVRSATD GNTSTTPPTS AKKRKLNSSS 120
SSSSSNSSNE REDFDSTSSS STPPQPRDSA SPSTSSFCLG VPVATSSHVP IQKKLRFEDT 180
LEFVGFDTKM AEESSSSSSS SSPTAATSQQ QQQQLKNKSI LISSVASVHH ANGLAKSSTT 240
VSSFANSKPG SAKKLVIKNF KDKPKLPENY TDETWQKLKE AVEAIQNSTS IKYNLEELYQ 300
AVENLCSYKI SANLYKQLRQ ICEDHIKAQI HQFREDSLDS VLFLKKIDRC WQNHCRQMIM 360
IRSIFLFLDR TYVLQNSMLP SIWDMGLELF RAHIISDQKV QTKTIDGILL LIERERNGEA 420
IDRSLLRSLL NMLSDLQIYQ DSFEQRFLQE TNRLYAAEGQ KLMQEREVPE YLHHVNKRLE 480
EEADRLITYL DQTTQKSLIA SVEKQLLGEH LTAILQKGLN SLLDENRIQD LSLLYQLFSR 540
VRGGVQVLLQ HWIEYIKAFG STIVINPEKD KTMVQELLDF KDKVDHIIDT CFLKNEKFIN 600
AMKEAFETFI NKRPNKPAEL IAKYVDSKLR AGNKEATDEE LEKMLDKIMI IFRFIYGKDV 660
FEAFYKKDLA KRLLVGKSAS VDAEKSMLSK LKHECGAAFT SKLEGMFKDM ELSKDIMIQF 720
KQYMQNQNVP GNIELTVNIL TMGYWPTYVP MEVHLPPEMV KLQEIFKTFY LGKHSGRKLQ 780
WQSTLGHCVL KAEFKEGKKE LQVSLFQTLV LLMFNEGEEF SLEEIKQATG IEDGELRRTL 840
QSLACGKARV LAKNPKGKDI EDGDKFICND DFKHKLFRIK INQIQMKETV EEQASTTERV 900
FQDRQYQIDA AIVRIMKMRK TLSHNLLVSE VYNQLKFPVK PADLKKRIES LIDRDYMERD 960
KENPNQYNYI A 971 
Gene Ontology
 GO:0031465; C:Cul4B-RING ubiquitin ligase complex; IEA:Compara.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0045732; P:positive regulation of protein catabolic process; IEA:Compara.
 GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. 
Interpro
 IPR016157; Cullin_CS.
 IPR016158; Cullin_homology.
 IPR001373; Cullin_N.
 IPR019559; Cullin_neddylation_domain.
 IPR016159; Cullin_repeat-like_dom.
 IPR011991; WHTH_DNA-bd_dom. 
Pfam
 PF00888; Cullin
 PF10557; Cullin_Nedd8 
SMART
 SM00182; CULLIN
 SM00884; Cullin_Nedd8 
PROSITE
 PS01256; CULLIN_1
 PS50069; CULLIN_2 
PRINTS