CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024247
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Universal stress protein MSMEG_3950/MSMEI_3859 
Protein Synonyms/Alias
 USP MSMEG_3950 
Gene Name
 MSMEG_3950, MSMEI_3859 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) 
NCBI Taxa ID
 246196 
Lysine Modification
Position
Peptide
Type
References
109RTLIDASKSAQMVVVpupylation[1, 2]
Reference
 [1] Expansion of the mycobacterial "PUPylome".
 Watrous J, Burns K, Liu WT, Patel A, Hook V, Bafna V, Barry CE 3rd, Bark S, Dorrestein PC.
 Mol Biosyst. 2010 Feb;6(2):376-85. [PMID: 20094657]
 [2] Proteome-wide identification of mycobacterial pupylation targets.
 Poulsen C, Akhter Y, Jeon AH, Schmitt-Ulms G, Meyer HE, Stefanski A, Stühler K, Wilmanns M, Song YH.
 Mol Syst Biol. 2010 Jul 13;6:386. [PMID: 20631680
Functional Description
  
Sequence Annotation
 CROSSLNK 109 109 Isoglutamyl lysine isopeptide (Lys-Gln)  
Keyword
 Complete proteome; Isopeptide bond; Reference proteome; Ubl conjugation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 294 AA 
Protein Sequence
MVQSATEYGI LVGVDSSAES DAAVRWAARE ASLHDAPITL MHVIAPVVVS WPAGPYMATV 60
LECQEENARH AIEQAQKVVA DCLGETHGLT VQTEIRKESV ARTLIDASKS AQMVVVGNRG 120
MGALGRVLLG STSTSLLHYA SGPVVVVHGD DQAAHDSRLP VLLGIDGSPA SEVATSHAFD 180
EASRRGVDLV ALHVWIDVGD IPPIGPTWEE QEETGRALLA ERLAGWQERY PDVKVHRRVE 240
RAQPAYWLLE EAKQAQLVVV GSHGRGGFTG MLLGSVSSRV AQSATTPVMV VRPR 294 
Gene Ontology
 GO:0006950; P:response to stress; IEA:InterPro. 
Interpro
 IPR014729; Rossmann-like_a/b/a_fold.
 IPR006015; Universal_stress_UspA.
 IPR006016; UspA. 
Pfam
 PF00582; Usp 
SMART
  
PROSITE
  
PRINTS
 PR01438; UNVRSLSTRESS.