UniProt Accession

 D6RFD7_MOUSE; D6RFD7 

Genbank Protein ID

 AC087184 

Genbank Nucleotide ID

  

Protein Name

 Medium-chain-specific acyl-CoA dehydrogenase, mitochondrial 

Protein Synonyms/Alias

  

Gene Name

 Acadm 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
30	QHSKAAHKQEPGLGF	acetylation	[1, 2]
30	QHSKAAHKQEPGLGF	succinylation	[2]

Reference

 [1] Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.
 Rardin MJ, Newman JC, Held JM, Cusack MP, Sorensen DJ, Li B, Schilling B, Mooney SD, Kahn CR, Verdin E, Gibson BW.
 Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6. [PMID: 23576753]
 [2] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 157 AA 

Protein Sequence

Gene Ontology

 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
 GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
 GO:0055007; P:cardiac muscle cell differentiation; IMP:MGI.
 GO:0009437; P:carnitine metabolic process; IMP:MGI.
 GO:0001889; P:liver development; IMP:MGI.
 GO:0009791; P:post-embryonic development; IMP:MGI.
 GO:0009409; P:response to cold; IMP:MGI.
 GO:0042594; P:response to starvation; IMP:MGI. 

Interpro

 IPR013786; AcylCoA_DH/ox_N. 

Pfam

  

SMART

  

PROSITE

  

PRINTS