| Tag | Content |
|---|
| CPLM ID | CPLM-013358 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Epsin-3 |
Protein Synonyms/Alias | EPS-15-interacting protein 3 |
Gene Name | Epn3 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 23 | NYSEAEIKVREATSN | ubiquitination | [1] | | 86 | TLLDYLLKTGSERVA | ubiquitination | [1] | | 107 | LYTIQTLKDFQYIDR | ubiquitination | [1] | | 117 | QYIDRDGKDQGVNVR | ubiquitination | [1] | | 135 | KQVMALLKDEERLRQ | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | |
Sequence Annotation | DOMAIN 12 144 ENTH.
REPEAT 202 221 UIM.
REPEAT 287 289 1.
REPEAT 310 312 2.
REPEAT 337 339 3.
REPEAT 353 355 4.
REPEAT 370 372 5.
REPEAT 495 497 1.
REPEAT 508 510 2.
REPEAT 605 607 3.
REGION 287 372 5 X 3 AA repeats of [DE]-P-W.
REGION 495 607 3 X 3 AA repeats of N-P-F.
BINDING 8 8 Phosphatidylinositol lipid headgroup (By
BINDING 11 11 Phosphatidylinositol lipid headgroup (By
BINDING 25 25 Phosphatidylinositol lipid headgroup (By
BINDING 30 30 Phosphatidylinositol lipid headgroup (By
BINDING 63 63 Phosphatidylinositol lipid headgroup (By
BINDING 73 73 Phosphatidylinositol lipid headgroup (By |
Keyword | Complete proteome; Cytoplasm; Cytoplasmic vesicle; Lipid-binding; Nucleus; Reference proteome; Repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 608 AA |
Protein Sequence | MTTSALRRQV KNIVHNYSEA EIKVREATSN DPWGPPSSLM SEIADLTFNT VAFAEVMGMV 60
WRRLNDSGKN WRHVYKALTL LDYLLKTGSE RVAHQCRENL YTIQTLKDFQ YIDRDGKDQG 120
VNVREKVKQV MALLKDEERL RQERTHALKT KERMALEGMG IGSGQLGFSR RSRGSPSSYT 180
SASSSPRYAS DLEQARPQTS GEEELQLQLA LAMSREEAEK GGRSWKGDDF PVANGAEPAG 240
QRRRDREPER EERKEEEKLK TSQSSILDLA DVFAPAPALP STHCSADPWD IPGLRPNTEP 300
SGSSWGPSAD PWSPVPSGNA LSRSQPWDLL PTLSSSEPWG RTPVLPSGPP ITDPWAPSSP 360
TPKLPSTGVD PWGASVETSN TSALGGASPF DPFAKPLEST EPMESRDSAQ ALPKGKSPSP 420
VELDPFGDSS PSCKQNGVKE TEALDLGVLG EALTQQPGKE ARPCRTPESF LGPSASSLVN 480
LDSLVKAPLA ARTRNPFLTG LSAPSPTNPF GAGEQGRPTL NQMRTGSPAL GLPPGGPVGV 540
PLGSMTYSAS LPLPLSSVPV GATLPASVSV FPQAGAFAPP PASLPQPLLP TSDPVGPLPP 600
QAGTNPFL 608 |
Gene Ontology | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell. GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell. GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. GO:0008289; F:lipid binding; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |