CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-044419
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Glucosylceramidase 
Protein Synonyms/Alias
  
Gene Name
 GBA 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
31EQKFQKVKGFGGAMTubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 449 AA 
Protein Sequence
MELSMGPIQA NHTGTGLLLT LQPEQKFQKV KGFGGAMTDA AALNILALSP PAQNLLLKSY 60
FSEEGIGYNI IRVPMASCDF SIRTYTYADT PDDFQLHNFS LPEEDTKLKI PLIHRALQLA 120
QRPVSLLASP WTSPTWLKTN GAVNGKGSLK GQPGDIYHQT WARYFVKFLD AYAEHKLQFW 180
AVTAENEPSA GLLSGYPFQC LGFTPEHQRD FIARDLGPTL ANSTHHNVRL LMLDDQRLLL 240
PHWAKVVLTD PEAAKYVHGI AVHWYLDFLA PAKATLGETH RLFPNTMLFA SEACVGSKFW 300
EQSVRLGSWD RGMQYSHSII TNLLYHVVGW TDWNLALNPE GGPNWVRNFV DSPIIVDITK 360
DTFYKQPMFY HLGHFSKFIP EGSQRVGLVA SQKNDLDAVA LMHPDGSAVV VVLNRSSKDV 420
PLTIKDPAVG FLETISPGYS IHTYLWRRQ 449 
Gene Ontology
 GO:0043202; C:lysosomal lumen; IEA:Compara.
 GO:0005765; C:lysosomal membrane; IEA:Compara.
 GO:0004348; F:glucosylceramidase activity; IEA:InterPro.
 GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
 GO:0006665; P:sphingolipid metabolic process; IEA:InterPro. 
Interpro
 IPR013780; Glyco_hydro_13_b.
 IPR001139; Glyco_hydro_30.
 IPR013781; Glyco_hydro_catalytic_dom.
 IPR017853; Glycoside_hydrolase_SF. 
Pfam
 PF02055; Glyco_hydro_30 
SMART
  
PROSITE
  
PRINTS
 PR00843; GLHYDRLASE30.