CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-001982
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Actin, larval muscle 
Protein Synonyms/Alias
 Actin-79B 
Gene Name
 Act79B 
Gene Synonyms/Alias
 CG7478 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
329APSTIKIKIIAPPERacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702
Functional Description
 Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. 
Sequence Annotation
 MOD_RES 3 3 N-acetylaspartate (By similarity).
 MOD_RES 45 45 Methionine sulfoxide.
 MOD_RES 48 48 Methionine sulfoxide.  
Keyword
 Acetylation; ATP-binding; Complete proteome; Cytoplasm; Cytoskeleton; Muscle protein; Nucleotide-binding; Oxidation; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 376 AA 
Protein Sequence
MCDEEASALV VDNGSGMCKA GFAGDDAPRA VFPSIVGRPR HQGVMVGMGQ KDCYVGDEAQ 60
SKRGILSLKY PIEHGIITNW DDMEKVWHHT FYNELRVAPE EHPVLLTEAP LNPKANREKM 120
TQIMFETFNS PAMYVAIQAV LSLYASGRTT GIVLDSGDGV SHTVPIYEGY ALPHAILRLD 180
LAGRDLTDYL MKILTERGYS FTTTAEREIV RDIKEKLCYV ALDFEQEMAT AAASTSLEKS 240
YELPDGQVIT IGNERFRTPE ALFQPSFLGM ESCGIHETVY QSIMKCDVDI RKDLYANNVL 300
SGGTTMYPGI ADRMQKEITA LAPSTIKIKI IAPPERKYSV WIGGSILASL STFQQMWISK 360
QEYDESGPGI VHRKCF 376 
Gene Ontology
 GO:0005884; C:actin filament; ISS:FlyBase.
 GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0005200; F:structural constituent of cytoskeleton; ISS:FlyBase.
 GO:0007010; P:cytoskeleton organization; ISS:FlyBase. 
Interpro
 IPR004000; Actin-related.
 IPR020902; Actin/actin-like_CS.
 IPR004001; Actin_CS. 
Pfam
 PF00022; Actin 
SMART
 SM00268; ACTIN 
PROSITE
 PS00406; ACTINS_1
 PS00432; ACTINS_2
 PS01132; ACTINS_ACT_LIKE 
PRINTS
 PR00190; ACTIN.