UniProt Accession

 CD151_HUMAN; P48509; A8KAK8; E9PI15; Q14826; Q86U54; Q96TE3 

Genbank Protein ID

 U14650; D29963; AF315942; BT007397; BT020132; CR456826; CR542098; AK293073; DQ074789; AP006621; AP006623; CH471158; BC001374; BC013302 

Genbank Nucleotide ID

 AAA87064.1; BAA06229.1; AAK14179.1; AAP36061.1; AAV38934.1; CAG33107.1; CAG46895.1; BAF85762.1; AAY68211.1; EAX02400.1; AAH01374.1; AAH13302.1 

Protein Name

 CD151 antigen 

Protein Synonyms/Alias

 GP27; Membrane glycoprotein SFA-1; Platelet-endothelial tetraspan antigen 3; PETA-3; Tetraspanin-24; Tspan-24; CD151 

Gene Name

 CD151 

Gene Synonyms/Alias

 TSPAN24 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
211	VEGGCITKLETFIQE	ubiquitination	[1]
249	CCLYRSLKLEHY***	ubiquitination	[2, 3]

Reference

 [1] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [3] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 

Functional Description

 Essential for the proper assembly of the glomerular and tubular basement membranes in kidney. 

Sequence Annotation

 LIPID 11 11 S-palmitoyl cysteine.
 LIPID 15 15 S-palmitoyl cysteine.
 LIPID 242 242 S-palmitoyl cysteine.
 LIPID 243 243 S-palmitoyl cysteine.
 CARBOHYD 159 159 N-linked (GlcNAc...) (Potential).  

Keyword

 Blood group antigen; Complete proteome; Deafness; Epidermolysis bullosa; Glycoprotein; Lipoprotein; Membrane; Palmitate; Polymorphism; Reference proteome; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 253 AA 

Protein Sequence

Gene Ontology

 GO:0005829; C:cytosol; TAS:Reactome.
 GO:0005887; C:integral to plasma membrane; TAS:ProtInc.
 GO:0007155; P:cell adhesion; NAS:ProtInc.
 GO:0016477; P:cell migration; IEA:Compara.
 GO:0030198; P:extracellular matrix organization; TAS:Reactome.
 GO:0031581; P:hemidesmosome assembly; TAS:Reactome.
 GO:0042098; P:T cell proliferation; IEA:Compara. 

Interpro

 IPR000301; Tetraspanin.
 IPR018499; Tetraspanin/Peripherin.
 IPR018503; Tetraspanin_CS.
 IPR008952; Tetraspanin_EC2. 

Pfam

 PF00335; Tetraspannin 

SMART

  

PROSITE

 PS00421; TM4_1 

PRINTS

 PR00259; TMFOUR.