| Tag | Content |
|---|
| CPLM ID | CPLM-007035 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | 60S ribosomal export protein NMD3 |
Protein Synonyms/Alias | Nonsense-mediated mRNA decay protein 3 |
Gene Name | NMD3 |
Gene Synonyms/Alias | YHR170W |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 467 | RQSVNLYKNREANVP | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit. Unlikely to play a significant role in nonsense-mediated mRNA decay (NMD). |
Sequence Annotation | MOTIF 399 415 Nuclear localization signal.
MOTIF 493 502 Nuclear export signal. |
Keyword | Complete proteome; Cytoplasm; Nucleus; Protein transport; Reference proteome; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 518 AA |
Protein Sequence | MEFTPIDPHQ HQNAATLLCC NCGTPIDGST GLVMCYDCIK LTVDITQGIP REANISFCRN 60
CERFLQPPGQ WIRAELESRE LLAICLRRLK GLTKVRLVDA SFIWTEPHSR RIRIKLTVQG 120
EAMTNTIIQQ TFEVEYIVIA MQCPDCARSY TTNTWRATVQ IRQKVPHKRT FLFLEQLILK 180
HNAHVDTISI SEAKDGLDFF YAQKNHAVKM IDFLNAVVPI KHKKSEELIS QDTHTGASTY 240
KFSYSVEIVP ICKDDLVVLP KKLAKSMGNI SQFVLCSKIS NTVQFMDPTT LQTADLSPSV 300
YWRAPFNALA DVTQLVEFIV LDVDSTGISR GNRVLADITV ARTSDLGVND QVYYVRSHLG 360
GICHAGDSVM GYFIANSNYN SDLFDGLNID YVPDVVLVKK LYQRKSKKSR HWKLKRMAKE 420
HKDIDASLDY NSRAQKQEME RAEKDYELFL QELEEDAELR QSVNLYKNRE ANVPPEEHEM 480
DEDEDEDAPQ INIDELLDEL DEMTLEDGVE NTPVESQQ 518 |
Gene Ontology | GO:0005829; C:cytosol; IDA:SGD. GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell. GO:0043023; F:ribosomal large subunit binding; IDA:SGD. GO:0015031; P:protein transport; IEA:UniProtKB-KW. GO:0000055; P:ribosomal large subunit export from nucleus; IMP:SGD. |
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Pfam | |
SMART | |
PROSITE | |
PRINTS | |