CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035534
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Nrap 
Protein Synonyms/Alias
  
Gene Name
 Nrap 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
372VSEVEYKKGLENSKGacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; LIM domain; Metal-binding; Reference proteome; Zinc. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1727 AA 
Protein Sequence
MNMQACSRCG YGVYPAEKVS CIDQTWHKAC FHCEVCKMML SVNNFVSHQK KPYCHAHNPK 60
NNTFTSVYRT PLNLTLKNSV AAMGGTDGKE DGEQFKSVLH WDMKSKAGAG AASRLMNERD 120
YWPGYGEGNT WCPGALPDPE IVRMVEARQS LREGYTEDGE QPQGKGSFPA MITPAYQRAK 180
AANQLASQVQ YKRGHDERVS TFTPVADTPE LLRANAGGQL QNDVRYTEDG GQQRGKGSFP 240
AMITPAYQIA KRAAELASDV RYHQQYHREM KGVASPVGAE GTMTKDSIDR CGQTYSEECE 300
EHRGKGSFPA MITPAYQNAK KANELASDIK YRQDFHKMKG AAHFHSLAAQ DNLVLQRAQN 360
VSKLVSEVEY KKGLENSKGH SINYCETPQF RNVSKISKFT SDNKYKENYQ THLRGHYEGV 420
GMDRRMLHAL KVGSLASNVA YKADYKHDVV DYNYPATATP FYQTTMKLAP LKDVNYRQNI 480
DRLKFSSVTN TPQIVQAKIN AQQLSHVNYR ADYERNKLNY TLPQDAPQML KAKANAQLFS 540
EVKYKEGWQK TKGKGFEMKL DAMSLLAAKA SGELASSIKY KEEYEKTKGR VLGTTDSKLL 600
HSLQVAKMSS EVEYKKGFEE SKTHFHLPMD MVNLRHAKKA QALASDLDYR KKLHDYTVLP 660
EDLKTQWAKK AHGLQSELQY KADLAWMKGV GWLTEGSLNL EQAKKAGQLV SEKHYRQKVD 720
ELKFTSVTDS SQMEHAKKSQ ELQNAVAYKA GNEQSVHQYT ISKDEPFFLR ARANAAQLSE 780
TLYKSSWEKQ KAKGFELRLD SLTFLTAKAK RDLASEVKYK EDYERSRGKL IGAKSAQGDS 840
QMSHSLQMSK LQSELEYKKG FEDTRSQYHV SLDMIHLAHA RQAQHLATDV GYRTASHCFT 900
ALPTDMKVEW AKKAYSLQSD NQYRADMKWM KGTGWVATGS LNVEQAKKAG ELISEKKYRQ 960
HPDALKFTSI KDTPEMVQAR ISYTQAVDRL YREQGENLKH HYTQTVDLPE VLLAKLNAMN 1020
ISETRYKESW SRLRDGGYKL RLDALPFQAA KASSEVISDY KYKEAFERMK GQLLGSRSLE 1080
DDLSLAHSVH ATSLQSDVNY KKGFEHSKAH FHLPLDMVTL VHAKKAQTLA SNQDYRHPLP 1140
QHTSLAEDLR LRCAKKAHKL QSENLYRSDL NFMRGVPCVI PGALEIEGRK KASELISESK 1200
YRQHPGSFKY TAVTDTPNLL HAKFSNQITN ERLYKAAGED ARHQYTMTLG LPEFIRAKTN 1260
AANLSEAKYK ESWHNLRAQG YKLTIDALPF QAARASGDIA SDFLYRHEFV KERGQLIGVR 1320
SVSDDPRLRH CQRMGQLQSE NWYRKEAASS QAQYHLPMDM VPLVHARKAQ ALASDHDYRT 1380
QCHEFTALPE DLKMAWAKKA HALQSEFRYK ADLMGMKGSG WLALQSPQIE SAKKAGELIS 1440
ETKYREKPDS IKFTTVVDSP DLVHARKSYE HCNERLYRLG DADSLHRYTP IADHPDFTRA 1500
RLNAMHLSDK VYRNSWEKNR AGGYDFRLDA IPFQTARASR DIASDFRYKE AFLRDRGLQI 1560
GYRSVNDDPR MRHFLRVGRL QSDNEYRKDF AKGRSQFHSR PDQPGFLQAK RSQQLASDVL 1620
YRQPLPQHTS DPEELGLKHA RKAHQLQSDV KYKSDLNLTR GVGWTPPGSY KVEMARRAAE 1680
LANRRGLGIQ GASVETEAVE LGDHRSRGVN PDASEILHIN RKKTLLM 1727 
Gene Ontology
 GO:0005916; C:fascia adherens; IEA:Compara.
 GO:0005927; C:muscle tendon junction; IEA:Compara.
 GO:0030016; C:myofibril; IEA:Compara.
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR013998; Nebulin.
 IPR000900; Nebulin_35r-motif.
 IPR001781; Znf_LIM. 
Pfam
 PF00412; LIM
 PF00880; Nebulin 
SMART
 SM00132; LIM
 SM00227; NEBU 
PROSITE
 PS00478; LIM_DOMAIN_1
 PS50023; LIM_DOMAIN_2
 PS51216; NEBULIN 
PRINTS
 PR00510; NEBULIN.