CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015218
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc finger protein 530 
Protein Synonyms/Alias
  
Gene Name
 ZNF530 
Gene Synonyms/Alias
 KIAA1508 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
274HECSECGKSFSRKTHubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
 May be involved in transcriptional regulation (By similarity). 
Sequence Annotation
 DOMAIN 14 94 KRAB.
 ZN_FING 239 261 C2H2-type 1.
 ZN_FING 267 289 C2H2-type 2.
 ZN_FING 295 317 C2H2-type 3.
 ZN_FING 323 345 C2H2-type 4.
 ZN_FING 351 373 C2H2-type 5.
 ZN_FING 379 401 C2H2-type 6.
 ZN_FING 407 429 C2H2-type 7.
 ZN_FING 435 457 C2H2-type 8.
 ZN_FING 463 485 C2H2-type 9.
 ZN_FING 491 513 C2H2-type 10.
 ZN_FING 519 541 C2H2-type 11.
 ZN_FING 547 569 C2H2-type 12.
 ZN_FING 575 597 C2H2-type 13.  
Keyword
 Complete proteome; DNA-binding; Metal-binding; Nucleus; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 599 AA 
Protein Sequence
MAAALRAPTQ QVFVAFEDVA IYFSQEEWEL LDEMQRLLYR DVMLENFAVM ASLGCWCGAV 60
DEGTPSAESV SVEELSQGRT PKADTSTDKS HPCEICTPVL RDILQMIELH ASPCGQKLYL 120
GGASRDFWMS SNLHQLQKLD NGEKLFKVDG DQASFMMNCR FHVSGKPFTF GEVGRDFSAT 180
SGLLQHQVTP TIERPHSRIR HLRVPTGRKP LKYTESRKSF REKSVFIQHQ RADSGERPYK 240
CSECGKSFSQ SSGFLRHRKA HGRTRTHECS ECGKSFSRKT HLTQHQRVHT GERPYDCSEC 300
GKSFRQVSVL IQHQRVHTGE RPYECSECGK SFSHSTNLYR HRSAHTSTRP YECSECGKSF 360
SHSTNLFRHW RVHTGVRPYE CSECGKAFSC NIYLIHHQRF HTGERPYVCS ECGKSFGQKS 420
VLIQHQRVHT GERPYECSEC GKVFSQSSGL FRHRRAHTKT KPYECSECEK SFSCKTDLIR 480
HQTVHTGERP YECSVCGKSF IRKTHLIRHQ TVHTNERPYE CDECGKSYSQ SSALLQHRRV 540
HTGERPYECR ECGKSFTRKN HLIQHKTVHT GERPYECSEC GKSFSQSSGL LRHRRVHVQ 599 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR001909; Krueppel-associated_box.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
 PF01352; KRAB
 PF00096; zf-C2H2 
SMART
 SM00349; KRAB
 SM00355; ZnF_C2H2 
PROSITE
 PS50805; KRAB
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS