CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-044254
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 KAT8 regulatory NSL complex subunit 1 
Protein Synonyms/Alias
  
Gene Name
 KANSL1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
180STSLNGGKRALTSSAacetylation[1]
262SSNLGGVKLEGKKSPubiquitination[2]
311RLQVVQAKQVERHIQubiquitination[2]
331FLEKTLSKLPNLESLubiquitination[2]
372EGLSNFLKSNSISEEubiquitination[3]
Reference
 [1] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1041 AA 
Protein Sequence
MAAMAPALTD AAAEAHHIRF KLAPPSSTLS PGSAENNGNA NILIAANGTK RKAIAAEDPS 60
LDFRNNPTKE DLGKLQPLVA SYLCSDVTSV PSKESLKLQG VFSKQTVLKS HPLLSQSYEL 120
RAELLGRQPV LEFSLENLRT MNTSGQTALP QAPVNGLAKK LTKSSTHSDH DNSTSLNGGK 180
RALTSSALHG GEMGGSESGD LKGGMTNCTL PHRSLDVEHT TLYSNNSTAN KSSVNSMEQP 240
ALQGSSRLSP GTDSSSNLGG VKLEGKKSPL SSILFSALDS DTRITALLRR QADIESRARR 300
LQKRLQVVQA KQVERHIQHQ LGGFLEKTLS KLPNLESLRP RSQLMLTRKA EAALRKAASE 360
TTTSEGLSNF LKSNSISEEL ERFTASGIAN LRCSEQAFDS DVTDSSSGGE SDIEEEELTR 420
ADPEQRHVPL RRRSEWKWAA DRAAIVSRWN WLQAHVSDLE YRIRQQTDIY KQIRANKGLI 480
VLGEVPPPEH TTDLFLPLSS EVKTDHGTDK LIESVSQPLE NHGARIIGHI SESLSTKSCG 540
ALRPVNGVIN TLQPVLADHI PGDSSDAEEQ LHKKQRLNLV SSSSDGTCVA ARTRPVLSCK 600
KRRLVRPNSI VPLSKKVHRN STIRPGCDVN PSCALCGSGS INTMPPEIHY EAPLLERLSQ 660
LDSCVHPVLA FPDDVPTSLH FQSMLKSQWQ NKPFDKIKPP KKLSLKHRAP MPGSLPDSAR 720
KDRHKLVSSF LTTAMLKHHT DMSSSSYLAA THHPPHSPLV RQLSTSSDSP APASSSSQVT 780
ASTSQPVRRR RGESSFDINN IVIPMSVAAT TRVEKLQYKE ILTPSWREVD LQSLKGSPDE 840
ENEEIEDLSD AAFAALHAKC EEMERARWLW TTSVPPQRRG SRSYRSSDGR TTPQLGSANP 900
STPQPASPDV SSSHSLSEYS HGQSPRSPIS PELHSAPLTP VARDTPRHLA SEDTRCSTPE 960
LGLDEQSVQP WERRTFPLAH SPQAECEDQL DAQERAARCT RRTSGSKTGR ETEAAPTSPP 1020
IVPLKSRHLV AAATAQRPTH R 1041 
Gene Ontology
 GO:0000123; C:histone acetyltransferase complex; IEA:InterPro. 
Interpro
 IPR026180; NSL1. 
Pfam
  
SMART
  
PROSITE
  
PRINTS