CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-009710
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Low affinity potassium transport system protein kup 
Protein Synonyms/Alias
 Kup system potassium uptake protein 
Gene Name
 kup 
Gene Synonyms/Alias
 trkD; b3747; JW5609 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
467AMIASLEKSPPVRVPacetylation[1]
496FALMHNLKHNKVLHEacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618
Functional Description
 Responsible for the low-affinity transport of potassium into the cell, with the probable concomitant uptake of protons (symport system). Can also transport cesium. 
Sequence Annotation
  
Keyword
 Cell inner membrane; Cell membrane; Complete proteome; Ion transport; Membrane; Potassium; Potassium transport; Reference proteome; Symport; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 622 AA 
Protein Sequence
MSTDNKQSLP AITLAAIGVV YGDIGTSPLY TLRECLSGQF GFGVERDAVF GFLSLIFWLL 60
IFVVSIKYLT FVMRADNAGE GGILTLMSLA GRNTSARTTS MLVIMGLIGG SFFYGEVVIT 120
PAISVMSAIE GLEIVAPQLD TWIVPLSIIV LTLLFMIQKH GTAMVGKLFA PIMLTWFLIL 180
AGLGLRSIIA NPEVLHALNP MWAVHFFLEY KTVSFIALGA VVLSITGVEA LYADMGHFGK 240
FPIRLAWFTV VLPSLTLNYF GQGALLLKNP EAIKNPFFLL APDWALIPLL IIAALATVIA 300
SQAVISGVFS LTRQAVRLGY LSPMRIIHTS EMESGQIYIP FVNWMLYVAV VIVIVSFEHS 360
SNLAAAYGIA VTGTMVLTSI LSTTVARQNW HWNKYFVALI LIAFLCVDIP LFTANLDKLL 420
SGGWLPLSLG TVMFIVMTTW KSERFRLLRR MHEHGNSLEA MIASLEKSPP VRVPGTAVYM 480
SRAINVIPFA LMHNLKHNKV LHERVILLTL RTEDAPYVHN VRRVQIEQLS PTFWRVVASY 540
GWRETPNVEE VFHRCGLEGL SCRMMETSFF MSHESLILGK RPWYLRLRGK LYLLLQRNAL 600
RAPDQFEIPP NRVIELGTQV EI 622 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0015079; F:potassium ion transmembrane transporter activity; IEA:HAMAP.
 GO:0015293; F:symporter activity; IEA:HAMAP. 
Interpro
 IPR003855; K+_transporter.
 IPR023051; K+_uptake_low_affin. 
Pfam
 PF02705; K_trans 
SMART
  
PROSITE
  
PRINTS