| Tag | Content |
|---|
| CPLM ID | CPLM-006247 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Mitochondrial import inner membrane translocase subunit TIM23 |
Protein Synonyms/Alias | Membrane import machinery protein MIM23; Mitochondrial protein import protein 3; Mitochondrial protein import protein MAS6 |
Gene Name | TIM23 |
Gene Synonyms/Alias | MAS6; MIM23; MPI3; YNR017W; N3180 |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 172 | TIDALRGKHDTAGSI | acetylation | [1] | | 190 | ALTGALFKSSKGLKP | acetylation | [1] |
|
Reference | [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C. Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [ PMID: 22865919] |
Functional Description | Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. |
Sequence Annotation | |
Keyword | Complete proteome; Membrane; Mitochondrion; Mitochondrion inner membrane; Protein transport; Reference proteome; Translocation; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 222 AA |
Protein Sequence | MSWLFGDKTP TDDANAAVGG QDTTKPKELS LKQSLGFEPN INNIISGPGG MHVDTARLHP 60
LAGLDKGVEY LDLEEEQLSS LEGSQGLIPS RGWTDDLCYG TGAVYLLGLG IGGFSGMMQG 120
LQNIPPNSPG KLQLNTVLNH ITKRGPFLGN NAGILALSYN IINSTIDALR GKHDTAGSIG 180
AGALTGALFK SSKGLKPMGY SSAMVAAACA VWCSVKKRLL EK 222 |
Gene Ontology | GO:0016021; C:integral to membrane; ISM:SGD. GO:0005744; C:mitochondrial inner membrane presequence translocase complex; IPI:SGD. GO:0005758; C:mitochondrial intermembrane space; TAS:Reactome. GO:0030943; F:mitochondrion targeting sequence binding; IMP:SGD. GO:0015450; F:P-P-bond-hydrolysis-driven protein transmembrane transporter activity; IEA:InterPro. GO:0015266; F:protein channel activity; IDA:SGD. GO:0030150; P:protein import into mitochondrial matrix; IMP:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |