CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024946
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein Spink5 
Protein Synonyms/Alias
 Serine peptidase inhibitor, Kazal type 5 
Gene Name
 Spink5 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
224RIRRDAEKELCKEFEacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1017 AA 
Protein Sequence
MKTATVPMLL TLAFYLTQDA AGEKGNQDPC MKFQAQMKNG TLTCPKGNNS SQSLNDIIFQ 60
SECILCKRAL EQGAPTKIMN VKVLSRANRA TDPAKLNCES FKQRRKDGDF ICPSDTSSVC 120
GTDGKTYRSR CELCAENAKS QNHVDVKSEG ECGSSHLETD MCSDFRAYVQ DGRLGCTRES 180
DPILGPDGRT HGNRCAMCAE LFLKEAKENA TRNRESRIRR DAEKELCKEF ENQVRNGRLF 240
CTRESDPIRG PDGKMHGNKC ALCAEIFMRQ FTEEKGKAEK NQKDAEERAK AKMEIQKRCS 300
EFQDRARNGT LFCTRENDPI RGLDGKTHGN LCSMCQAFFK TEAEEKKAEA GSRNRRGSEE 360
SETYAKLCDE YRKARKNGQL YCTRENAPIR GPDGKIHGNT CSMCQAFFIQ EDKARAKVKR 420
EAAKEMCSEF RNQARNGMLM CTRENDPVVG PDGKRHSNKC AMCASVFLLE EEEKKKDDKT 480
EKVDAGKAKK EAVQELCRKY HTQLRNGPLR CTRRNNPIEG LDGKMYKNAC FMCWAFFQQE 540
AKKSGAGFRP KVKREVKVDC SEYLALSKRG EIFCTRENDP VRGPDGKTHG NKCAMCKAVF 600
KKENEERKRK EGENQRITSG ESSSGGNPKA KDECAQYRES MKHGQLSCTR ESDPVRGVDG 660
EHYNNKCVMC KELLQKEMEE TNKNSASRSN GTGSATGKDV CDQFRSQMKN GKLLCTRESD 720
PTRGPDGAMH GNKCAMCKER LEKEAAEKKK KEDEEKRNTE TNKSDKEDKC HEYRSMQLDG 780
RLICTRENDP VRDADGKMHV NKCAMCQMMF EREANERKMR EENSRSQPTN EAKDQCGEVH 840
NSVEDAKPRP ARSSLPSIRG ISKDECSEFQ NLMKNEKLTC PETDDPVRGA DGTFYQNKCH 900
MCRDVLKNEA MKRSGLQEKS SDIRSTKEGD PEFSSSSRDS DMCKNYRILP RMGYLCPKNL 960
NPVCGDDGQT YSNPCMLCHE NLMRQTNTRI HKQGACEESS NLKTVSTGTP ASEKMMQ 1017 
Gene Ontology
 GO:0005938; C:cell cortex; IEA:Compara.
 GO:0005829; C:cytosol; IEA:Compara.
 GO:0005789; C:endoplasmic reticulum membrane; IEA:Compara.
 GO:0097209; C:epidermal lamellar body; IEA:Compara.
 GO:0048471; C:perinuclear region of cytoplasm; IEA:Compara.
 GO:0030414; F:peptidase inhibitor activity; IMP:MGI.
 GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:Compara.
 GO:0009913; P:epidermal cell differentiation; IEA:Compara.
 GO:0045861; P:negative regulation of proteolysis; IMP:MGI.
 GO:0030155; P:regulation of cell adhesion; IMP:MGI. 
Interpro
 IPR002350; Kazal_dom. 
Pfam
 PF00050; Kazal_1
 PF07648; Kazal_2 
SMART
 SM00280; KAZAL 
PROSITE
 PS00282; KAZAL_1
 PS51465; KAZAL_2 
PRINTS