CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-023457
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Gastrulation defective protein 1 homolog 
Protein Synonyms/Alias
  
Gene Name
 CG5543 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
10RGKISFGKIKLNVNVacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702
Functional Description
  
Sequence Annotation
 REPEAT 180 219 WD 1.
 REPEAT 227 268 WD 2.
 REPEAT 281 321 WD 3.
 REPEAT 330 369 WD 4.
 REPEAT 377 416 WD 5.
 REPEAT 422 467 WD 6.
 REPEAT 470 510 WD 7.  
Keyword
 Complete proteome; Reference proteome; Repeat; WD repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 655 AA 
Protein Sequence
MQRGKISFGK IKLNVNVPPA EPRSNETEAE DAKESTEASG NGGGFKKMDK EQMIRQIEDV 60
AEDLESQHLK EVMGISGFGR KAAKVFDINE QIEKARVTRP GMDKKREESK PKEDDQKDEE 120
EEDVIGPLPP AVTTDKEKAT KESSKDEDSD DDDYSSDEDS DDEQSLAKRI PYTHEVQMQH 180
GSRAVLALAG DPSGARLVSG SIDYDMCFWD FAGMDSSMRS FRQLQPCENH PIRSLQYSVT 240
GDMILVISGN AQAKVLDRDG FEKLECCKGD QYISDMSRTK GHVAQLTSGC WHPFNREQFL 300
TAALDGTLRI WQGLKSKEQL QVIKTRAQGG LRTNAASCNF NRDATLIAAG CVDGSIQTWD 360
TRKMFVNTTH CVRDAHQKGS EITSIVFSYM GQQLATRSND ETMKLWDLRQ FKQPLHTWTN 420
LFSRYDTTDC CFSPDDRLLV TGESLPKGQA EANLYFYSTK SYEEVQRIPV SNAHVVKTLW 480
HPKLNQLFVS CGNGTIKCYY DEHRSIRGAK LCVVKTHRKR QPMEMVGVSQ IITPHALPLF 540
RQEKSRTSRK RMEKARMDPV KSQRPDLPIT SGQGGRVASS GGTLSSYVIR NLGLSKRVDD 600
DQDPREAILK YAKDAAENPY WIAPAYKQTQ PKAIFSEKLP ADEPATKKPK TEADK 655 
Gene Ontology
 GO:0022008; P:neurogenesis; IMP:FlyBase. 
Interpro
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR019775; WD40_repeat_CS.
 IPR017986; WD40_repeat_dom. 
Pfam
 PF00400; WD40 
SMART
 SM00320; WD40 
PROSITE
 PS00678; WD_REPEATS_1
 PS50082; WD_REPEATS_2
 PS50294; WD_REPEATS_REGION 
PRINTS