UniProt Accession

 SUHB_ECOLI; P0ADG4; P22783; P77511; Q8X2E6 

Genbank Protein ID

 M34828; U00096; AP009048 

Genbank Nucleotide ID

 AAA67506.1; AAC75586.1; BAA16427.1 

Protein Name

 Inositol-1-monophosphatase 

Protein Synonyms/Alias

 I-1-Pase; IMPase; Inositol-1-phosphatase 

Gene Name

 suhB 

Gene Synonyms/Alias

 ssyA; b2533; JW2517 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
14	IAVRAARKAGNLIAK	acetylation	[1, 2]
21	KAGNLIAKNYETPDA	acetylation	[2]
45	DFVTNVDKAAEAVII	acetylation	[2]
160	LATGFPFKAKQYATT	acetylation	[2]
251	AGNPRVVKAMLANMR	acetylation	[2]
266	DELSDALKR******	acetylation	[2]

Reference

 [1] Comprehensive profiling of protein lysine acetylation in Escherichia coli.
 Zhang K, Zheng S, Yang JS, Chen Y, Cheng Z.
 J Proteome Res. 2013 Feb 1;12(2):844-51. [PMID: 23294111]
 [2] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

  

Sequence Annotation

 REGION 86 89 Substrate binding (By similarity).
 METAL 67 67 Magnesium 1 (By similarity).
 METAL 84 84 Magnesium 1 (By similarity).
 METAL 84 84 Magnesium 2 (By similarity).
 METAL 86 86 Magnesium 1; via carbonyl oxygen (By
 METAL 87 87 Magnesium 2 (By similarity).
 METAL 212 212 Magnesium 2 (By similarity).
 BINDING 67 67 Substrate (By similarity).
 BINDING 183 183 Substrate (By similarity).
 BINDING 212 212 Substrate (By similarity).  

Keyword

 3D-structure; Complete proteome; Hydrolase; Magnesium; Metal-binding; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 267 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:EcoliWiki.
 GO:0047954; F:glycerol-2-phosphatase activity; IDA:EcoCyc.
 GO:0008934; F:inositol monophosphate 1-phosphatase activity; IDA:EcoCyc.
 GO:0052832; F:inositol monophosphate 3-phosphatase activity; IEA:EC.
 GO:0052833; F:inositol monophosphate 4-phosphatase activity; IEA:EC.
 GO:0031403; F:lithium ion binding; IDA:EcoliWiki.
 GO:0000287; F:magnesium ion binding; IDA:EcoCyc.
 GO:0046855; P:inositol phosphate dephosphorylation; IDA:EcoliWiki.
 GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro. 

Interpro

 IPR020583; Inositol_monoP_metal-BS.
 IPR000760; Inositol_monophosphatase.
 IPR020550; Inositol_monophosphatase_CS.
 IPR022337; Inositol_monophosphatase_SuhB. 

Pfam

 PF00459; Inositol_P 

SMART

  

PROSITE

 PS00629; IMP_1
 PS00630; IMP_2 

PRINTS

 PR00377; IMPHPHTASES.
 PR01959; SBIMPHPHTASE.