| Tag | Content |
|---|
| CPLM ID | CPLM-013304 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Proteasome subunit beta type-10 |
Protein Synonyms/Alias | Low molecular mass protein 10; Macropain subunit MECl-1; Multicatalytic endopeptidase complex subunit MECl-1; Proteasome MECl-1; Proteasome subunit beta-2i |
Gene Name | Psmb10 |
Gene Synonyms/Alias | Lmp10; Mecl1 |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 101 | TTRMAASKMELHALS | acetylation | [1] |
|
Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides (By similarity). |
Sequence Annotation | ACT_SITE 40 40 Nucleophile (By similarity). |
Keyword | Complete proteome; Cytoplasm; Hydrolase; Nucleus; Protease; Proteasome; Reference proteome; Threonine protease. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 273 AA |
Protein Sequence | MLKQAVEHRG GFSFENCQRN ASLEHVLPGL RVPLARKTGT TIAGLVFRDG VILGADTRAT 60
NDSVVADKSC EKIHFIAPKI YCCGAGVAAD TEMTTRMAAS KMELHALSTG REPRVATVTR 120
ILRQTLFRYQ GHVGASLIVG GVDLNGPQLY SVHPHGSYSR LPFTALGSGQ DAAVALLEDR 180
FQPNMTLEAA QELLVEAITA GILGDLGSGG SVDACVITAG GAKLQRALSS PIEPVQRAGQ 240
YRFAPGTTPV QTQEVRALTL ELLEETVQAM EVE 273 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0005839; C:proteasome core complex; ISS:UniProtKB. GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW. GO:0000902; P:cell morphogenesis; IEA:Compara. GO:0051603; P:proteolysis involved in cellular protein catabolic process; IEA:InterPro. GO:0042098; P:T cell proliferation; IEA:Compara. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |