CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031344
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Importin subunit alpha 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
23NYRMKSYKNNALNPEubiquitination[1]
54KREQQLFKRRNVELVubiquitination[1]
139DRFVEFLKRNENCTLubiquitination[1]
359SPKESIRKEACWTISubiquitination[1]
Reference
 [1] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 
Functional Description
 Functions in nuclear protein import (By similarity). 
Sequence Annotation
  
Keyword
 Protein transport; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 541 AA 
Protein Sequence
MKSYVSETMA SPGKDNYRMK SYKNNALNPE EMRRRREEEG IQLRKQKREQ QLFKRRNVEL 60
VNEEAAMFDS LLMDSYVSST TGESVITREM VEMLFSDDSD LQLATTQKFR KLLSKEPSPP 120
IDEVINTPRV VDRFVEFLKR NENCTLQFEA AWALTNIASG TSQQTKIVIE AGAVPIFIEL 180
LNSDFEDVQE QAVWALGNIA GDSSVCRDYV LNCSILNPLL TLLTKSTRLT MTRNAVWALS 240
NLCRGKNPPP EFAKVSPCLP VLSRLLFSSD SDLLADACWA LSYLSDGPNE KIQAVIDSGV 300
CRRLVELLMH NDYKVASPAL RAVGNIVTGD DIQTQVILNC SALPCLLHLL SSPKESIRKE 360
ACWTISNITA GNRAQIQAVI DANIFPVLIE ILQKAEFRTR KEAAWAITNA TSGGTPEQIR 420
YLVSLGCIKP LCDLLTVMDS KIVQVALNGL ENILRLGEQE GKRSGSGVNP YCGLIEEAYG 480
LDKIEFLQSH ENQEIYQKAF DLIEHYFGVE DDDSSLAPQV DETQQQFIFQ QPEAPMEGFQ 540
L 541 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:InterPro.
 GO:0005634; C:nucleus; IEA:InterPro.
 GO:0008565; F:protein transporter activity; IEA:InterPro.
 GO:0006606; P:protein import into nucleus; IEA:InterPro. 
Interpro
 IPR011989; ARM-like.
 IPR016024; ARM-type_fold.
 IPR000225; Armadillo.
 IPR002652; Importin-a_IBB.
 IPR024931; Importing_su_alpha. 
Pfam
 PF00514; Arm
 PF01749; IBB 
SMART
 SM00185; ARM 
PROSITE
 PS50176; ARM_REPEAT
 PS51214; IBB 
PRINTS