CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026015
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Aconitate hydratase (Citrate hydro-lyase) (Aconitase) 
Protein Synonyms/Alias
  
Gene Name
 citB 
Gene Synonyms/Alias
 GK1347 
Created Date
 July 27, 2013 
Organism
 Geobacillus kaustophilus (strain HTA426) 
NCBI Taxa ID
 235909 
Lysine Modification
Position
Peptide
Type
References
26VDGRVITKEHVENLAacetylation[1]
34EHVENLAKWGTPEMKacetylation[1]
48KDIDVPFKPSRVILQacetylation[1]
237TATDLALKVTQVLRKacetylation[1]
551SEPIGKGKDGSDVYFacetylation[1]
569WPSMEEVKDVVKRAVacetylation[1]
642TGLRVVGKFGDSVTTacetylation[1]
671AGQYLISKGVDPKDFacetylation[1]
676ISKGVDPKDFNSYGSacetylation[1]
733YDACMKYKQDGTGLVacetylation[1]
766GTFLLGIKTVIAESFacetylation[1]
834TNPDTGEKKEFEVIVacetylation[1]
Reference
 [1] Proteomic analysis of acetylation in thermophilic Geobacillus kaustophilus.
 Lee DW, Kim D, Lee YJ, Kim JA, Choi JY, Kang S, Pan JG.
 Proteomics. 2013 Aug;13(15):2278-82. [PMID: 23696451] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Iron; Iron-sulfur; Lyase; Metal-binding. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 871 AA 
Protein Sequence
MSRLPYSIKV LLESVLRQVD GRVITKEHVE NLAKWGTPEM KDIDVPFKPS RVILQDFTGV 60
PVVVDLASMR KAMADLGGDP YEINPEIPVD LVIDHSVQVD RYGSDDALEY NMDLEFKRNA 120
ERYKFLKWAQ KAFDNYRAVP PATGIVHQVN LEYLASVVHA VEGENGEYEA FPDTLVGTDS 180
HTTMINGLGV LGWGVGGIEA EAGMLGQPSY FPVPEVIGVR LTGKLPDGAT ATDLALKVTQ 240
VLRKKGVVGK FVEFFGPGVA TLPLADRATI ANMAPEYGAT CGFFPVDAEA LDYLRLTGRD 300
EHHVQVVEAY CKANGLFYTP DAPEPVFTDV VEINLSEIET NLSGPKRPQD LIPLSKMKQS 360
FRDAVKAPQG NQGFGLTEAD LEREITVELN GEQVKLKTGA VVIAAITSCT NTSNPYVLVA 420
AGLVAKKAVE KGLQVPKYVK TSLAPGSKVV TGYLRDSGLL PYLEQLGFNI VGYGCTTCIG 480
NSGPLAPELE KALAESDLLV TSVLSGNRNF EGRIHPLVKG NYLASPPLVV AYALAGTVDI 540
DLLSEPIGKG KDGSDVYFRD IWPSMEEVKD VVKRAVDPEL FRKEYERVFD GNPRWNAIET 600
TDEPLYQWDE NSTYIQNPPF FEGLSPEVRK VEPLTGLRVV GKFGDSVTTD HISPAGSIGK 660
NTPAGQYLIS KGVDPKDFNS YGSRRGNHEV MMRGTFANIR IRNQIAPGTE GGYTTYWPTG 720
EVMSMYDACM KYKQDGTGLV VIAGKDYGMG SSRDWAAKGT FLLGIKTVIA ESFERIHRSN 780
LVLMGVLPLQ FKEGENAETL GLTGKEVFDI HIDENVKPRD LVKVTATNPD TGEKKEFEVI 840
VRFDSEVEID YYRHGGILQM VLREKLAKVK Q 871 
Gene Ontology
 GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.
 GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.
 GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. 
Interpro
 IPR015931; Acnase/IPM_dHydase_lsu_aba_1/3.
 IPR015937; Acoase/IPM_deHydtase.
 IPR001030; Acoase/IPM_deHydtase_lsu_aba.
 IPR015928; Aconitase/3IPM_dehydase_swvl.
 IPR006249; Aconitase/Fe_reg_prot_2.
 IPR015934; Aconitase/Fe_reg_prot_2/AcnD.
 IPR015932; Aconitase/IPMdHydase_lsu_aba_2.
 IPR018136; Aconitase_4Fe-4S_BS.
 IPR000573; AconitaseA/IPMdHydase_ssu_swvl. 
Pfam
 PF00330; Aconitase
 PF00694; Aconitase_C 
SMART
  
PROSITE
 PS00450; ACONITASE_1
 PS01244; ACONITASE_2 
PRINTS
 PR00415; ACONITASE.