| Tag | Content |
|---|
| CPLM ID | CPLM-004179 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Anion exchange protein 2 |
Protein Synonyms/Alias | AE 2; Anion exchanger 2; Band 3-related protein; B3RP; Non-erythroid band 3-like protein; Solute carrier family 4 member 2 |
Gene Name | Slc4a2 |
Gene Synonyms/Alias | Ae2 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 654 | EPKSAQDKALLQMVE | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Plasma membrane anion exchange protein of wide distribution. |
Sequence Annotation | REGION 704 1237 Membrane (anion exchange).
MOD_RES 112 112 Phosphoserine (By similarity).
MOD_RES 131 131 Phosphoserine (By similarity).
MOD_RES 144 144 Phosphoserine (By similarity).
MOD_RES 439 439 Phosphoserine (By similarity).
LIPID 1169 1169 S-palmitoyl cysteine (By similarity).
CARBOHYD 855 855 N-linked (GlcNAc...) (Potential).
CARBOHYD 866 866 N-linked (GlcNAc...) (Potential).
CARBOHYD 878 878 N-linked (GlcNAc...) (Potential). |
Keyword | Alternative splicing; Anion exchange; Antiport; Complete proteome; Glycoprotein; Ion transport; Lipoprotein; Membrane; Palmitate; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1237 AA |
Protein Sequence | MSSAPRRPAS GADSLHTPEP ESLSPGTPGF PEQEEDELRT LGVERFEEIL QEAGSRGGEE 60
PGRSYGEEDF EYHRQSSHHI HHPLSTHLPP DARRRKTPQG PGRKPRRRPG ASPTGETPTI 120
EEGEEDEEEA SEAEGFRAPP QQPSPATTPS AVQFFLQEDE GAERKPERTS PSPPTQTPHQ 180
EAAPRASKGA QTGTLVEEMV AVASATAGGD DGGAAGRPLT KAQPGHRSYN LQERRRIGSM 240
TGVEQALLPR VPTDESEAQT LATADLDLMK SHRFEDVPGV RRHLVRKNAK GSTQAAREGR 300
EPGPTPRARP RAPHKPHEVF VELNELLLDK NQEPQWRETA RWIKFEEDVE EETERWGKPH 360
VASLSFRSLL ELRRTLAHGA VLLDLDQQTL PGVAHQVVEQ MVISDQIKAE DRANVLRALL 420
LKHSHPSDEK EFSFPRNISA GSLGSLLGHH HAQGTESDPH VTEPLIGGVP ETRLEVDRER 480
ELPPPAPPAG ITRSKSKHEL KLLEKIPENA EATVVLVGCV EFLSRPTMAF VRLREAVELD 540
AVLEVPVPVR FLFLLLGPSS ANMDYHEIGR SISTLMSDKQ FHEAAYLADE RDDLLTAINA 600
FLDCSVVLPP SEVQGEELLR SVAHFQRQML KKREEQGRLL PPGAGLEPKS AQDKALLQMV 660
EVAGAAEDDP LRRTGRPFGG LIRDVRRRYP HYLSDFRDAL DPQCLAAVIF IYFAALSPAI 720
TFGGLLGEKT KDLIGVSELI MSTALQGVVF CLLGAQPLLV IGFSGPLLVF EEAFFSFCSS 780
NELEYLVGRV WIGFWLVFLA LLMVALEGSF LVRFVSRFTQ EIFAFLISLI FIYETFYKLI 840
KIFQEHPLHG CSGSNDSEAG SSSSSNMTWA TTILVPDNSS ASGQSGQEKP RGQPNTALLS 900
LVLMAGTFFI AFFLRKFKNS RFFPGRIRRV IGDFGVPIAI LIMVLVDYSI EDTYTQKLSV 960
PSGFSVTAPD KRGWVINPLG EKTPFPVWMM VASLLPAVLV FILIFMETQI TTLIISKKER 1020
MLQKGSGFHL DLLLIVAMGG ICALFGLPWL AAATVRSVTH ANALTVMSKA VAPGDKPKIQ 1080
EVKEQRVTGL LVALLVGLSM VIGDLLRQIP LAVLFGIFLY MGVTSLNGIQ FYERLHLLLM 1140
PPKHHPDVTY VKKVRTMRMH LFTALQLLCL ALLWAVMSTA ASLAFPFILI LTVPLRMVVL 1200
TRIFTEREMK CLDANEAEPV FDECEGVDEY NEMPMPV 1237 |
Gene Ontology | GO:0016323; C:basolateral plasma membrane; IDA:MGI. GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0015108; F:chloride transmembrane transporter activity; IDA:UniProtKB. GO:0005452; F:inorganic anion exchanger activity; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |