Tag | Content |
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CPLM ID | CPLM-002002 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Fatty acid-binding protein, intestinal |
Protein Synonyms/Alias | Fatty acid-binding protein 2; Intestinal-type fatty acid-binding protein; I-FABP |
Gene Name | Fabp2 |
Gene Synonyms/Alias | Fabpi |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
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8 | MAFDGTWKVDRNENY | acetylation | [1] | 17 | DRNENYEKFMEKMGI | acetylation | [1] | 47 | TITQEGNKFTVKESS | acetylation | [1] | 93 | EGNKLVGKFKRVDNG | acetylation | [1] |
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Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long- chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor (By similarity). |
Sequence Annotation | BINDING 83 83 Fatty acid. BINDING 107 107 Fatty acid. MOD_RES 2 2 N-acetylalanine. |
Keyword | 3D-structure; Acetylation; Complete proteome; Cytoplasm; Direct protein sequencing; Lipid-binding; Reference proteome; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 132 AA |
Protein Sequence | MAFDGTWKVD RNENYEKFME KMGINVVKRK LGAHDNLKLT ITQEGNKFTV KESSNFRNID 60 VVFELGVDFA YSLADGTELT GTWTMEGNKL VGKFKRVDNG KELIAVREIS GNELIQTYTY 120 EGVEAKRIFK KE 132 |
Gene Ontology | |
Interpro | |
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SMART | |
PROSITE | |
PRINTS | |