CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-042976
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Putative ATP-dependent RNA helicase TDRD9 
Protein Synonyms/Alias
  
Gene Name
 TDRD9 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
45YIFEVEGKPHSVEEYubiquitination[1]
167SPVPGYRKIILSTNIubiquitination[1]
214LRLSWASKTSCNQRKubiquitination[1]
238YCYRLVHKDFWDNSIubiquitination[1]
264PLGSTILKVKLLDMGubiquitination[1, 2]
266GSTILKVKLLDMGEPubiquitination[1, 2]
297ERTILLLKEVGALAVubiquitination[1, 2, 3]
377HLDGYRNKVNFSGSSubiquitination[1]
385VNFSGSSKSDCIALVubiquitination[1]
396IALVEAFKTWKACRQubiquitination[1]
411TGELRYPKDELNWGRubiquitination[1, 2]
425RLNYIQIKRIREVAEubiquitination[1]
438AELYEELKTRISQFNubiquitination[1]
462MDQEYIYKQRFILQVubiquitination[1]
530FRQCGQVKSIVFDGAubiquitination[1]
538SIVFDGAKAFVEFSRubiquitination[1]
591VQGMNVSKLRNTRVNubiquitination[1]
603RVNVDFQKQTVDPMQubiquitination[1, 2]
831ILRAAINKLVCDGPNubiquitination[1]
841CDGPNGCKCLGPERVubiquitination[1, 2, 3]
867LGLFCQSKPREKIVPubiquitination[1]
879IVPKWHEKPYEWNQVubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 918 AA 
Protein Sequence
XRTNSRFVKV VLMSATISCK EFADYFAVPV QNKMNPAYIF EVEGKPHSVE EYYLNDLEHI 60
HHSKLSPHLL EEPVITKDIY EVAVSLIQMF DDLDMKESGN KAWSGAQFVL ERSSVLVFLP 120
GLGEINYMHE LLTSLVHKRL QVYPLHSSVA LEEQNNVFLS PVPGYRKIIL STNIAESSVT 180
VPDVKYVIDF CLTRTLVCDE DTNYQSLRLS WASKTSCNQR KGRAGRVSRG YCYRLVHKDF 240
WDNSIPDHVV PEMLRCPLGS TILKVKLLDM GEPRALLATA LSPPGLSDIE RTILLLKEVG 300
ALAVSGQRED ENPHDGELTF LGRVLAQLPV NQQLGKLIVL GHVFGCLDEC LIIAAALSLK 360
NFFAMPFRQH LDGYRNKVNF SGSSKSDCIA LVEAFKTWKA CRQTGELRYP KDELNWGRLN 420
YIQIKRIREV AELYEELKTR ISQFNMHVDS RRPVMDQEYI YKQRFILQVV LAGAFYPNYF 480
TFGQPDEEMA VRELAGKDPK TTVVLKHIPP YGFLYYKQLQ SLFRQCGQVK SIVFDGAKAF 540
VEFSRNPTER FKTLPAVYMA IKMSQLKVSL ELSVHSAEEI EGKVQGMNVS KLRNTRVNVD 600
FQKQTVDPMQ VSFNTSDRSQ TVTDLLLTID VTEVVEVGHF WGYRIDENNS EILKKLTAEI 660
NQLTLVPLPT HPHPDLVCLA PFADFDKQRY FRAQVLYVSG NSAEVFFVDY GNKSHVDLHL 720
LMEIPCQFLE LPFQALEFKI CKMRPSAKSL VCGKHWSDGA SQWFASLVSG CTLLVKVFSV 780
VHSVLHVDVY QYSGVQDAIN IRDVLIQQGY AELTEESYES KVNILRAAIN KLVCDGPNGC 840
KCLGPERVAQ LQDIARQKLL GLFCQSKPRE KIVPKWHEKP YEWNQVDPKL VMEQADRESS 900
RGKNTFLYQL HKLVVLGT 918 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0004386; F:helicase activity; IEA:InterPro.
 GO:0003676; F:nucleic acid binding; IEA:InterPro. 
Interpro
 IPR007502; Helicase-assoc_dom.
 IPR001650; Helicase_C.
 IPR027417; P-loop_NTPase.
 IPR002999; Tudor. 
Pfam
 PF04408; HA2
 PF00271; Helicase_C
 PF00567; TUDOR 
SMART
 SM00847; HA2
 SM00490; HELICc
 SM00333; TUDOR 
PROSITE
 PS51194; HELICASE_CTER
 PS50304; TUDOR 
PRINTS