CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038806
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Ptprd 
Protein Synonyms/Alias
  
Gene Name
 Ptprd 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
868RAESESRKSSLPNSKubiquitination[1]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Hydrolase; Protein phosphatase; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1479 AA 
Protein Sequence
PPRFTRTPVD QTGVSGGVAS FICQATGDPR PKIVWNKKGK KVSNQRFEVI EFDDGSGSVL 60
RIQPLRTPRD EAIYECVASN NVGEISVSTR LTVLREDQIP RGFPTIDMGP QLKVVERTRT 120
ATMLCAASGN PDPEITWFKD FLPVDTSNNN GRIKQLRSAS VYSTLLTGAL QIEQSEESDQ 180
GKYECVATNS AGTRYSAPAN LYVRDLHEVR RVPPRFSIPP TNHEIMPGGS VNITCVAVGS 240
PMPYVKWMLG AEDLTPEDDM PIGRNVLELN DVRQSANYTC VAMSTLGVIE AVAQITVKAL 300
PKPPGTPVVT ESTATSITLT WDSGNPEPVS YYIIQHKPKN SEEPYKEIDG IATTRYSVAG 360
LSPYSDYEFR VVAVNNIGRG PASEPVLTQT SEQAPSSAPR DVQARMLSST TILVQWKEPE 420
EPNGQIQGYR VYYTMDPTQH VNNWMKHNVA DSQITTIGNL VPQKTYSVKV LAFTSIGDGP 480
LSSDIQVITQ TGVPGQPLNF KAEPESETSI LLSWTPPRSD TIASYELVYR DGDQGEEQRI 540
TIEPGTSYRL QGLKPNSLYY FRLSARSPQG LGASTAEISA RTMQSMFAKN FHVKAVMKTS 600
VLLSWEIPEN YNSAMPFKIL YDDGKMVEEV DGRATQKLIV NLKPEKSYSF VLTNRGNSAG 660
GLQHRVTAKT APDVLRTKPA FIGKTNLDGM ITVQLPDVPA NENIKGYYII IVPLKKSRGK 720
FIKPWESPDE MELDELLKEI SRKRRSIRYG REVELKPYIA AHFDVLPTEF TLGDDKHYGG 780
FTNKQLQSGQ EYVFFVLAVM DHAESKMYAT SPYSDPVVSM DLDPQPITDE EEGLIWVVGP 840
VLAVVFIICI VIAILLYKRK RAESESRKSS LPNSKEVPSH HPTDPVELRR LNFQTPGMAS 900
HPPIPILELA DHIERLKAND NLKFSQEYES IDPGQQFTWE HSNLEVNKPK NRYANVIAYD 960
HSRVLLSAIE GIPGSDYVNA NYIDGYRKQN AYIATQGSLP ETFGDFWRMI WEQRSATVVM 1020
MTKLEERSRV KCDQYWPSRG TETHGLVQVT LLDTVELATY CVRTFALYKN GSSEKREVRQ 1080
FQFTAWPDHG VPEHPTPFLA FLRRVKTCNP PDAGPMVVHC SAGVGRTGCF IVIDAMLERI 1140
KHEKTVDIYG HVTLMRAQRN YMVQTEDQYI FIHDALLEAV TCGNTEVPAR NLYAYIQKLT 1200
QIETGENVTG MELEFKRLAS SKAHTSRFIS ANLPCNKFKN RLVNIMPYES TRVCLQPIRG 1260
VEGSDYINAS FLDGYRQQKA YIATQGPLAE TTEDFWRMLW EHNSTIVVML TKLREMGREK 1320
CHQYWPAERS ARYQYFVVDP MAEYNMPQYI LREFKVTDAR DGQSRTVRQF QFTDWPEQGV 1380
PKSGEGFIDF IGQVHKTKEQ FGQDGPISVH CSAGVGRTGV FITLSIVLER MRYEGVVDIF 1440
QTVKMLRTQR PAMVQTEDQY QFCYRAALEY LGSFDHYAT 1479 
Gene Ontology
 GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
 GO:0035335; P:peptidyl-tyrosine dephosphorylation; IEA:GOC. 
Interpro
 IPR003961; Fibronectin_type3.
 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR013098; Ig_I-set.
 IPR003598; Ig_sub2.
 IPR000387; Tyr/Dual-sp_Pase.
 IPR016130; Tyr_Pase_AS.
 IPR000242; Tyr_Pase_rcpt/non-rcpt. 
Pfam
 PF00041; fn3
 PF07679; I-set
 PF00102; Y_phosphatase 
SMART
 SM00060; FN3
 SM00408; IGc2
 SM00194; PTPc 
PROSITE
 PS50853; FN3
 PS50835; IG_LIKE
 PS00383; TYR_PHOSPHATASE_1
 PS50056; TYR_PHOSPHATASE_2
 PS50055; TYR_PHOSPHATASE_PTP 
PRINTS
 PR00700; PRTYPHPHTASE.