CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041602
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Activity-dependent neuroprotector homeobox protein 
Protein Synonyms/Alias
 RCG32280, isoform CRA_i 
Gene Name
 Adnp 
Gene Synonyms/Alias
 rCG_32280 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
1036WKNSSYGKVEGFWSKacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; DNA-binding; Homeobox; Nucleus; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1103 AA 
Protein Sequence
MFQLPVNNLG SLRKARKTVK KILSDIGLEY CKEHIEDFKQ FEPNDFYLKN TTWEDVGLWD 60
PSLTKNQDYR TKPFCCSACP FSSKFFSAYK SHFRNVHSED FENRILLNCP YCTFNADKKT 120
LETHIKIFHA PNSSAPSSSL STFKDKNKND GLKPKQADNV EQAVYYCKKC TYRDPLYEIV 180
RKHIYREHFQ HVAAPYIAKA GEKSLNGAVS LGTNAREECN IHCKRCLFMP KSYEALVQHV 240
IEDHERIGYQ VTAMIGHTNV VVPRAKPLML IAPKPQEKKS MGLPPRISSL ASGNVRSLPS 300
QQMVNRLSIP KPNLNSTGVN MMSNVHLQQN NYGVKSVGQS YGVGQSVRLG LGGNAPVSIP 360
QQSQSVKQLL PSGNGRSYGL GAEQRPPAAA RYSLQTANTS SLPPGQVKSP SVSQSQASRV 420
LGQSSSKPPP AATGPPPSNH CATQKWKICT ICNELFPENV YSVHFEKEHK AEKVPAVANY 480
IMKIHNFTSK CLYCNRYLPT DTLLNHMLIH GLSCPYCRST FNDVEKMAAH MRMVHIDEEM 540
GPKTDSTLSF DLTLQQGSHT NIHLLVTTYN LRDAPAESVA YHAQNNAPVP PKPQPKVQEK 600
ADVPVKSSPQ AAVPYKKDVG KTLCPLCFSI LKGPISDALA HHLRERHQVI QTVHPVEKKL 660
TYKCIHCLGV YTSNMTASTI TLHLVHCRGV GKTQNGQDKT NAPSRLNQSP GLAPVKRTYE 720
QMEFPLLKKR KLEDENDSPG CFEEKPEEPV VLALDPKGHE DDSYEARKSF LTKYFNKQPY 780
PTRREIEKLA ASLWLWKSDI ASHFSNKRKK CVRDCEKYKP GVLLGFNMKE LNKVKHEMDF 840
DAEWLFENHD EKASRVNASK TVDKKLNLGK EDDSFSDSFE HLEEESNGSG GPFDPVFEVE 900
PKIPSDNAEE PVPKVIPEGA LESEKLDQKE EEDGSKYETI HLTEERAKLM HDASDSEVDQ 960
DDVVEWKDGA SPSESGPGSR QVSDFEDNTC EMKPGTWSDE SSQSEDARSS KPAAKKKATV 1020
QDDTEQLKWK NSSYGKVEGF WSKDQSQWEN ASENAERLPN PQIEWQNSTI DSEDGEQFDS 1080
MTDGVADPMH GSLTGVKLSS QQA 1103 
Gene Ontology
 GO:0005615; C:extracellular space; IEA:Compara.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003682; F:chromatin binding; IEA:Compara.
 GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Compara. 
Interpro
 IPR001356; Homeodomain.
 IPR009057; Homeodomain-like.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like. 
Pfam
 PF00046; Homeobox 
SMART
 SM00389; HOX
 SM00355; ZnF_C2H2 
PROSITE
 PS50071; HOMEOBOX_2
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS