CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025782
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 MKIAA4014 protein 
Protein Synonyms/Alias
  
Gene Name
 Akr1c13 
Gene Synonyms/Alias
 mKIAA4014 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
27ALGFGTYKPKEVPKSubiquitination[1]
29GFGTYKPKEVPKSKSacetylation[2]
163CKDAGLVKSIGVSNFubiquitination[1]
227ALGTQRYKEWVDQNSubiquitination[1]
248PVLCDVAKKNKRSPAubiquitination[1]
275VPLAQSFKENEMRENubiquitination[1]
303KTLDGLNKNFRYLPAubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 325 AA 
Protein Sequence
ETMSSKQHCV KLNDGHLIPA LGFGTYKPKE VPKSKSLEAA CLALDVGYRH VDTAYAYQVE 60
EEIGQAIQSK IKAGVVKRED LFITTKLWCT CFRPELVKPA LEKSLKKLQL DYVDLYIMHY 120
PVPMKSGDND FPVNEQGKSL LDTVDFCDTW ERLEECKDAG LVKSIGVSNF NHRQLERILN 180
KPGLKYKPVC NQVECHLYLN QRKLLDYCES KDIVLVAYGA LGTQRYKEWV DQNSPVLLND 240
PVLCDVAKKN KRSPALIALR YLIQRGIVPL AQSFKENEMR ENLQVFGFQL SPEDMKTLDG 300
LNKNFRYLPA EFLVDHPEYP FVEEY 325 
Gene Ontology
 GO:0004033; F:aldo-keto reductase (NADP) activity; ISS:MGI.
 GO:0006805; P:xenobiotic metabolic process; TAS:MGI. 
Interpro
 IPR001395; Aldo/ket_red.
 IPR018170; Aldo/ket_reductase_CS.
 IPR020471; Aldo/keto_reductase_subgr.
 IPR023210; NADP_OxRdtase_dom. 
Pfam
 PF00248; Aldo_ket_red 
SMART
  
PROSITE
 PS00798; ALDOKETO_REDUCTASE_1
 PS00062; ALDOKETO_REDUCTASE_2 
PRINTS
 PR00069; ALDKETRDTASE.