CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-009136
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 BTB/POZ domain-containing protein 1 
Protein Synonyms/Alias
 Glucose signal-repressing protein 
Gene Name
 Btbd1 
Gene Synonyms/Alias
 Gsrp 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
58LYNWQATKASLKERFubiquitination[1]
394QIIEYEKKQTLGQNDubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). 
Sequence Annotation
 DOMAIN 75 151 BTB.  
Keyword
 Complete proteome; Cytoplasm; Reference proteome; Ubl conjugation pathway. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 488 AA 
Protein Sequence
MASLGSAAAG EPATGAEAEP GPPAPPPPPP PPPAPSPSAL GPLLPLQREP LYNWQATKAS 60
LKERFAFLFN SELLSDVRFV LGKGRGAAAA GGPQRIPAHR FVLAAGSAVF DAMFNGGMAT 120
TSAEIELPDV EPAAFLALLR FLYSDEVQIG PETVMTTLYT AKKYAVPALE AHCVEFLTKH 180
LRADNAFMLL TQARLFDEPQ LASLCLDTID KSTVDAISAE GFTDIDIDTL CAVLERDTLS 240
IRESRLFGAI VRWAEAECQR QQLAVTFGNK QKVLGKALSL IRFPLMTIEE FAAGPAQSGI 300
LSDREVVNLF LHFTVNPKPR VEYIDRPRCC LRGKECCINR FQQVESRWGY SGTSDRIRFT 360
VNRRISVVGF GLYGSIHGPT DYQVNIQIIE YEKKQTLGQN DTGFSCDGTA NTFRVMFKEP 420
IEILPNVCYT ACATLKGPDS HYGTKGLKKV VHETPAASKT VFLFFSSPGN NNGTSIEDGQ 480
IPEIIFYT 488 
Gene Ontology
 GO:0000932; C:cytoplasmic mRNA processing body; IDA:UniProtKB.
 GO:0043234; C:protein complex; IEA:Compara.
 GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway. 
Interpro
 IPR011705; BACK.
 IPR000210; BTB/POZ-like.
 IPR011333; BTB/POZ_fold.
 IPR013069; BTB_POZ.
 IPR012983; PHR. 
Pfam
 PF07707; BACK
 PF00651; BTB
 PF08005; PHR 
SMART
 SM00875; BACK
 SM00225; BTB 
PROSITE
 PS50097; BTB 
PRINTS