CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015615
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Inactive ubiquitin carboxyl-terminal hydrolase 54 
Protein Synonyms/Alias
 Inactive ubiquitin-specific peptidase 54 
Gene Name
 USP54 
Gene Synonyms/Alias
 C10orf29 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
324EPDIYQEKLSQVRDVubiquitination[1]
334QVRDVRSKDLGSSTDubiquitination[1]
Reference
 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661
Functional Description
 Has no peptidase activity. 
Sequence Annotation
 MOD_RES 227 227 Phosphoserine (By similarity).
 MOD_RES 671 671 Phosphoserine.  
Keyword
 Alternative splicing; Coiled coil; Complete proteome; Phosphoprotein; Polymorphism; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1684 AA 
Protein Sequence
MDTEFGASSF FHSPASCHES HSSLSPESSA PQHSSPSRSA LKLLTSVEVD NIEPSAFHRQ 60
GLPKAPGWTE KNSHHSWEPL DAPEGKLQGS RCDNSSCSKL PPQEGRGIAQ EQLFQEKKDP 120
ANPSPVMPGI ATSERGDEHS LGCSPSNSSA QPSLPLYRTC HPIMPVASSF VLHCPDPVQK 180
TNQCLQGQSL KTSLTLKVDR GSEETYRPEF PSTKGLVRSL AEQFQRMQGV SMRDSTGFKD 240
RSLSGSLRKN SSPSDSKPPF SQGQEKGHWP WAKQQSSLEG GDRPLSWEES TEHSSLALNS 300
GLPNGETSSG GQPRLAEPDI YQEKLSQVRD VRSKDLGSST DLGTSLPLDS WVNITRFCDS 360
QLKHGAPRPG MKSSPHDSHT CVTYPERNHI LLHPHWNQDT EQETSELESL YQASLQASQA 420
GCSGWGQQDT AWHPLSQTGS ADGMGRRLHS AHDPGLSKTS TAEMEHGLHE ARTATPCRGL 480
SRECGEDEQY SAENLRRISR SLSGTVVSER EEAPVSSHSF DSSNVRKPLE TGHRCSSSSS 540
LPVIHDPSVF LLGPQLYLPQ PQFLSPDVLM PTMAGEPNRL PGTSRSVQQF LAMCDRGETS 600
QGAKYTGRTL NYQSLPHRSR TDNSWAPWSE TNQHIGTRFL TTPGCNPQLT YTATLPERSK 660
GLQVPHTQSW SDLFHSPSHP PIVHPVYPPS SSLHVPLRSA WNSDPVPGSR TPGPRRVDMP 720
PDDDWRQSSY ASHSGHRRTV GEGFLFVLSD APRREQIRAR VLQHSQW 767 
Gene Ontology
 GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
 GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. 
Interpro
 IPR001394; Peptidase_C19. 
Pfam
 PF00443; UCH 
SMART
  
PROSITE
 PS00972; UCH_2_1
 PS00973; UCH_2_2
 PS50235; UCH_2_3 
PRINTS