CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026363
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Catenin (Cadherin associated protein), alpha 1 
Protein Synonyms/Alias
 Catenin (Cadherin-associated protein), alpha 1, isoform CRA_b; Protein Ctnna1 
Gene Name
 Ctnna1 
Gene Synonyms/Alias
 Catna1; rCG_49560 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
186ALKPEVDKLNIMAAKacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 908 AA 
Protein Sequence
MTAVHTGNIN FKWDPKSLEI RTLAVERLLE PLVTQVTTLV NTNSKGPSNK KRGRSKKAHV 60
LAASVEQATE NFLEKGDKIA KESQFLKEEL VAAVDDVRKQ GDLMKSAAGE FADDPCSSVK 120
RGNMVRAARA LLSAVTRLLI LADMADVYKL LVQLKVVEDG ILKLRNAGNE QDLGIQYRAL 180
KPEVDKLNIM AAKRQQELKD VGHRDQMAAA RGILQKNVPI LYTASQACLQ HPDVAAYKAN 240
RDLIYKQLQQ AVTGISNAAQ ATASDDASQQ QGGGGGGGEL AYALNNFDKQ IIVDPLSFSE 300
ERFRPSLEER LESIISGAAL MADSSCTRDD RRERIVAECN AVRQALQDLL SEYMGNAGRK 360
ERSDALNSAI DKMTKKTRDL RRQLRKAVMD HVSDSFLETN VPLLVLIEAA KNGNEKEVKE 420
YAQVFREHAN KLIEVANLAC SISNNEEGVK LVRMSASQLE ALCPQVINAA LALAAKPQSK 480
LAQENMDLFK EQWEKQVRVL TDAVDDITSI DDFLAVSENH ILEDVNKCVI ALQEKDVDGL 540
DRTAGAIRGR AARVIHVVTS EMDNYEPGVY TEKVLEATKL LSNTVMPRFT EQVEAAVEAL 600
SSDPAQPMDE NEFIDASRLV YDGIRDIRKA VLMIRTPEEL DDSDFETEDF DVRSRTSVQT 660
EDDQLIAGQS ARAIMAQLPQ EQKAKIAEQV ASFQEEKSKL DAEVSKWDDS GNDIIVLAKQ 720
MCMIMMEMTD FTRGKGPLKN TSDVISAAKK IAEAGSRMDK LGRTIADHCP DSACKQDLLA 780
YLQRIALYCH QLNICSKVKA EVQNLGGELV VSGVDSAMSL IQAAKNLMNA VVQTVKASYV 840
ASTKYQKSQG MASLNLPAVS WKMKAPEKKP LVKREKQDET QTKIKRASQK KHVNPVQALS 900
EFKAMDSI 908 
Gene Ontology
 GO:0001669; C:acrosomal vesicle; IDA:RGD.
 GO:0015629; C:actin cytoskeleton; IEA:InterPro.
 GO:0016342; C:catenin complex; IEA:Compara.
 GO:0005913; C:cell-cell adherens junction; IDA:RGD.
 GO:0014704; C:intercalated disc; IEA:Compara.
 GO:0030027; C:lamellipodium; IEA:Compara.
 GO:0005886; C:plasma membrane; IDA:RGD.
 GO:0005915; C:zonula adherens; IEA:Compara.
 GO:0005198; F:structural molecule activity; IEA:InterPro.
 GO:0007568; P:aging; IEP:RGD.
 GO:0043297; P:apical junction assembly; IEA:Compara.
 GO:0031103; P:axon regeneration; IEP:RGD.
 GO:0007155; P:cell adhesion; IEA:InterPro.
 GO:0071681; P:cellular response to indole-3-methanol; IEA:Compara.
 GO:0007163; P:establishment or maintenance of cell polarity; IEA:Compara.
 GO:0016264; P:gap junction assembly; IMP:RGD.
 GO:0008584; P:male gonad development; IEP:RGD.
 GO:0043066; P:negative regulation of apoptotic process; IEA:Compara.
 GO:0007406; P:negative regulation of neuroblast proliferation; IEA:Compara.
 GO:0042475; P:odontogenesis of dentin-containing tooth; IEP:RGD.
 GO:0001541; P:ovarian follicle development; IEP:RGD.
 GO:0045880; P:positive regulation of smoothened signaling pathway; IEA:Compara.
 GO:0051291; P:protein heterooligomerization; IPI:RGD.
 GO:0043627; P:response to estrogen stimulus; IEP:RGD. 
Interpro
 IPR001033; Alpha_catenin.
 IPR006077; Vinculin/catenin.
 IPR000633; Vinculin_CS. 
Pfam
 PF01044; Vinculin 
SMART
  
PROSITE
 PS00663; VINCULIN_1 
PRINTS
 PR00805; ALPHACATENIN.