CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029164
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Glutathione S-transferase Mu 4 
Protein Synonyms/Alias
  
Gene Name
 GSTM4 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
141LDAFPNLKDFISRFEubiquitination[1, 2, 3]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 202 AA 
Protein Sequence
MLGSLLAQLS FPGFPSIQLP YLIDGAHKIT QSNAILCYIA RKHNLCGETE EEKIRVDILE 60
NQAMDVSNQL ARVCYSPDFE KLKPEYLEEL PTMMQHFSQF LGKRPWFVGD KITFVDFLAY 120
DVLDLHRIFE PNCLDAFPNL KDFISRFEVM PPSSFLFDAP CSVTSFQMLS QSWSYIKNNL 180
HLLSAGFMPG TLPSTLYLSC GI 202 
Gene Ontology
 GO:0004364; F:glutathione transferase activity; IEA:InterPro. 
Interpro
 IPR010987; Glutathione-S-Trfase_C-like.
 IPR004045; Glutathione_S-Trfase_N.
 IPR017933; Glutathione_S_Trfase/Cl_chnl_C.
 IPR004046; GST_C.
 IPR003081; GST_mu.
 IPR012336; Thioredoxin-like_fold. 
Pfam
 PF00043; GST_C
 PF02798; GST_N 
SMART
  
PROSITE
 PS50405; GST_CTER
 PS50404; GST_NTER 
PRINTS
 PR01267; GSTRNSFRASEM.