| Tag | Content |
|---|
| CPLM ID | CPLM-015071 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Zinc finger and SCAN domain-containing protein 25 |
Protein Synonyms/Alias | Zinc finger protein 498 |
Gene Name | ZSCAN25 |
Gene Synonyms/Alias | ZNF498 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 111 | EHGPESGKALAAMVE | ubiquitination | [1] | | 128 | TERALEAKAVPCHRQ | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | May be involved in transcriptional regulation (By similarity). |
Sequence Annotation | DOMAIN 42 124 SCAN box.
ZN_FING 348 370 C2H2-type 1.
ZN_FING 375 397 C2H2-type 2.
ZN_FING 403 425 C2H2-type 3.
ZN_FING 431 453 C2H2-type 4.
ZN_FING 459 480 C2H2-type 5.
ZN_FING 486 508 C2H2-type 6.
ZN_FING 514 536 C2H2-type 7; degenerate. |
Keyword | Alternative splicing; Complete proteome; DNA-binding; Metal-binding; Nucleus; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 544 AA |
Protein Sequence | MLKEHPEMAE APQQQLGIPV VKLEKELPWG RGREDPSPET FRLRFRQFRY QEAAGPQEAL 60
RELQELCRRW LRPELHTKEQ ILELLVLEQF LTILPREFYA WIREHGPESG KALAAMVEDL 120
TERALEAKAV PCHRQGEQEE TALCRGAWEP GIQLGPVEVK PEWGMPPGEG VQGPDPGTEE 180
QLSQDPGDET RAFQEQALPV LQAGPGLPAV NPRDQEMAAG FFTAGSQGLG PFKDMALAFP 240
EEEWRHVTPA QIDCFGEYVE PQDCRVSPGG GSKEKEAKPP QEDLKGALVA LTSERFGEAS 300
LQGPGLGRVC EQEPGGPAGS APGLPPPQHG AIPLPDEVKT HSSFWKPFQC PECGKGFSRS 360
SNLVRHQRTH EEKSYGCVEC GKGFTLREYL MKHQRTHLGK RPYVCSECWK TFSQRHHLEV 420
HQRSHTGEKP YKCGDCWKSF SRRQHLQVHR RTHTGEKPYT CECGKSFSRN ANLAVHRRAH 480
TGEKPYGCQV CGKRFSKGER LVRHQRIHTG EKPYHCPACG RSFNQRSILN RHQKTQHRQE 540
PLVQ 544 |
Gene Ontology | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. GO:0016032; P:viral reproduction; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |