UniProt Accession

 J3KTF5_HUMAN; J3KTF5 

Genbank Protein ID

 AC008481 

Genbank Nucleotide ID

  

Protein Name

 Evolutionarily conserved-signaling intermediate in Toll pathway, mitochondrial 

Protein Synonyms/Alias

  

Gene Name

 ECSIT 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
22	QLLNIFPKEVFRPRN	ubiquitination	[1]
85	MLKLVRLKLWFPRFM	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 223 AA 

Protein Sequence

Gene Ontology

 GO:0005739; C:mitochondrion; IEA:Compara.
 GO:0005667; C:transcription factor complex; IEA:Compara.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Compara.
 GO:0004871; F:signal transducer activity; IEA:Compara.
 GO:0030509; P:BMP signaling pathway; IEA:Compara.
 GO:0001707; P:mesoderm formation; IEA:Compara. 

Interpro

 IPR010418; ECSIT. 

Pfam

 PF06239; ECSIT 

SMART

  

PROSITE

  

PRINTS