UniProt Accession

 GLOD4_HUMAN; Q9HC38; D3DTG9; D3DTH1; Q96B89; Q9H3J8; Q9HC37; Q9NVN1 

Genbank Protein ID

 AF177342; AF177343; AF061730; AK001488; CH471108; CH471108; CH471108; CH471108; CH471108; BC008605; BC015848 

Genbank Nucleotide ID

 AAG17986.1; AAG17987.1; AAG43141.1; EAW90645.1; EAW90646.1; EAW90647.1; EAW90649.1; EAW90650.1; AAH08605.1; AAH15848.1 

Protein Name

 Glyoxalase domain-containing protein 4 

Protein Synonyms/Alias

  

Gene Name

 GLOD4 

Gene Synonyms/Alias

 C17orf25; CGI-150; My027 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
30	YRDVLGMKVLRHEEF	ubiquitination	[1, 2, 3]
183	GYADNQCKLELQGVK	ubiquitination	[2]
190	KLELQGVKGGVDHAA	ubiquitination	[1, 2]
219	PDLEDLMKRENQKIL	ubiquitination	[2]
224	LMKRENQKILTPLVS	ubiquitination	[2, 3]
283	DDAMAADKSDEWFAK	ubiquitination	[2]

Reference

 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 

Functional Description

  

Sequence Annotation

  

Keyword

 3D-structure; Alternative splicing; Complete proteome; Direct protein sequencing; Mitochondrion; Polymorphism; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 313 AA 

Protein Sequence

Gene Ontology

 GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. 

Interpro

 IPR025870; Glyoxalase-like_dom. 

Pfam

 PF12681; Glyoxalase_2 

SMART

  

PROSITE

  

PRINTS