CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032539
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Heat shock protein 60 
Protein Synonyms/Alias
 Heat shock protein, putative 
Gene Name
 TGGT1_025360, TGME49_047550, TGVEG_004250 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Toxoplasma gondii 
NCBI Taxa ID
 5811 
Lysine Modification
Position
Peptide
Type
References
127AIFREGCKAVDAGMNacetylation[1, 2]
388HSDYEKEKLQERLARacetylation[1, 2]
Reference
 [1] Lysine acetylation is widespread on proteins of diverse function and localization in the protozoan parasite Toxoplasma gondii.
 Jeffers V, Sullivan WJ Jr.
 Eukaryot Cell. 2012 Jun;11(6):735-42. [PMID: 22544907]
 [2] Protein intrinsic disorder in the acetylome of intracellular and extracellular Toxoplasma gondii.
 Xue B, Jeffers V, Sullivan WJ, Uversky VN.
 Mol Biosyst. 2013 Apr 5;9(4):645-57. [PMID: 23403842] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Chaperone; Complete proteome; Nucleotide-binding; Reference proteome; Stress response. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 575 AA 
Protein Sequence
MLARASARVA KCNPGNVFQV RHASSKEIRF GCDARNQMLA GCNRLADAVG VTLGPKGRNV 60
VIEQPYGSPK ITKDGVTVAK SIELGNRMMN LGAQLVKQVA STTNDIAGDG TTTATLLARA 120
IFREGCKAVD AGMNPMDLLR GINLAVEKVL AHLNSVTKNV TTSEEIFNVA TISANGDKVI 180
GKLIADAMEK VGRDGTITVS EGKTLTHELE LVEGLKFDRG YISPYFITNS KEQKVELEKP 240
FVLLYDKRIS SVKSILPVLE FIVQNQGSLL IIAEDVDSEA LATMVVNKLR LGLKICAVKA 300
PGFGDHRKAM LHDIAVMTGG QVVTEETGGS LEDAHQMPQM LGRAKSVTVT KDTTLVIEGG 360
GEKATIDERC DQIRVSMEQT HSDYEKEKLQ ERLARMTGGV AVIKVGGASE VEVGEAKDRI 420
QDALCATKAA VEEGIVPGGG TALLYASETL KTIETTNYDQ KVGVGIVRNA CKQPCKTIAD 480
NAGHEGAVVV GNLLREADPT KGFNAQTGEY VDMMAAGIID PTKVVKTALS DAASVASLMT 540
TTEAAVVEAK EEKPDEPMGG GMPMGGMGGG MGGMY 575 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:InterPro.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0042026; P:protein refolding; IEA:InterPro.
 GO:0006950; P:response to stress; IEA:UniProtKB-KW. 
Interpro
 IPR018370; Chaperonin_Cpn60_CS.
 IPR001844; Chaprnin_Cpn60.
 IPR002423; Cpn60/TCP-1.
 IPR027409; GroEL-like_apical_dom.
 IPR027413; GROEL-like_equatorial. 
Pfam
 PF00118; Cpn60_TCP1 
SMART
  
PROSITE
 PS00296; CHAPERONINS_CPN60 
PRINTS
 PR00298; CHAPERONIN60.