CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032406
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Small ubiquitin-related modifier 1 
Protein Synonyms/Alias
  
Gene Name
 SUMO1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
7*MSDQEAKPSTEDLGubiquitination[1, 2]
16STEDLGDKKEGEYIKubiquitination[1, 2]
17TEDLGDKKEGEYIKLubiquitination[1, 2]
23KKEGEYIKLKVIGQDubiquitination[2]
25EGEYIKLKVIGQDSSubiquitination[1, 2, 3]
37DSSEIHFKVKMTTHLubiquitination[1, 2, 3, 4]
39SEIHFKVKMTTHLKKubiquitination[2]
46KMTTHLKKLKESYCQubiquitination[1, 2]
48TTHLKKLKESYCQRQubiquitination[1, 2, 3, 4]
Reference
 [1] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789]
 [4] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 146 AA 
Protein Sequence
MSDQEAKPST EDLGDKKEGE YIKLKVIGQD SSEIHFKVKM TTHLKKLKES YCQRQGVPMN 60
SLRFLFEGQR IADNHTPKEA QWPTPAILAL WEAEAGWITA GQELRPAWAT WRNLISTKNR 120
KSSQLGMEEE DVIEVYQEQT GGHSTV 146 
Gene Ontology
  
Interpro
 IPR022617; SUMO.
 IPR000626; Ubiquitin.
 IPR019955; Ubiquitin_supergroup. 
Pfam
 PF11976; Rad60-SLD 
SMART
 SM00213; UBQ 
PROSITE
 PS50053; UBIQUITIN_2 
PRINTS