CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-001399
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Target of Myb protein 1 
Protein Synonyms/Alias
  
Gene Name
 Tom1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
106LVRTILPKNNPPTIVubiquitination[1]
382SSLADQRKGVKYEAPubiquitination[1]
385ADQRKGVKYEAPQTTubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 May be involved in intracellular trafficking. Probable association with membranes. 
Sequence Annotation
 DOMAIN 20 152 VHS.
 DOMAIN 215 303 GAT.
 MOD_RES 1 1 N-acetylmethionine (By similarity).
 MOD_RES 11 11 Phosphoserine (By similarity).
 MOD_RES 160 160 Phosphoserine (By similarity).
 MOD_RES 164 164 Phosphothreonine (By similarity).
 MOD_RES 174 174 Phosphothreonine.
 MOD_RES 176 176 Phosphoserine.
 MOD_RES 180 180 Phosphoserine.
 MOD_RES 355 355 Phosphoserine (By similarity).
 MOD_RES 462 462 Phosphoserine (By similarity).  
Keyword
 Acetylation; Alternative splicing; Complete proteome; Cytoplasm; Membrane; Phosphoprotein; Protein transport; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 492 AA 
Protein Sequence
MDFLLGNPFS SPVGQRIEKA TDGSLQSEDW ALNMEICDII NETEEGPKDA FRAVKKRIMG 60
NKNFHEVMLA LTVLETCVKN CGHRFHVLVA NQDFVENVLV RTILPKNNPP TIVHDKVLNL 120
IQSWADAFRS SPDLTGVVAV YEDLRRKGLE FPMTDLDMLS PIHTPQRTVF NSETPSRQNS 180
VSSNTSQRGD LSQHATPLPT PAVLPGDSPI TPTPEQIGKL RSELEMVSGN VRVMSEMLTE 240
LVPTQVEPAD LELLQELNRT CRAMQQRILE LIPRISNEQL TEELLMINDN LNNVFLRHER 300
FERFRTGQTA KASSEAELAT DLIDMGPDPA ATNNLSSQLA GMNLGSRSVR AGLQSLETSG 360
HLEDDFDMFA LTRGSSLADQ RKGVKYEAPQ TTDGLAGALD ARQQSTGAIP ATQARIMEDI 420
EQWLSTDVGN SAEEPSGVTS EEFDKFLEER AKAADRLPNL ASPSAEGPPR PSPGTAPRRK 480
TQEKDDDMLF AL 492 
Gene Ontology
 GO:0005829; C:cytosol; ISS:UniProtKB.
 GO:0005769; C:early endosome; ISS:UniProtKB.
 GO:0016020; C:membrane; ISS:UniProtKB.
 GO:0006886; P:intracellular protein transport; IEA:InterPro. 
Interpro
 IPR008942; ENTH_VHS.
 IPR004152; GAT.
 IPR014645; TOM1.
 IPR002014; VHS.
 IPR018205; VHS_subgr. 
Pfam
 PF03127; GAT
 PF00790; VHS 
SMART
 SM00288; VHS 
PROSITE
 PS50909; GAT
 PS50179; VHS 
PRINTS