CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-018476
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc finger protein 622 
Protein Synonyms/Alias
  
Gene Name
 Znf622 
Gene Synonyms/Alias
 D15Ertd806e; Zfp622 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
114RVELLNAKNLEKGLGubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 May behave as an activator of the bound transcription factor, MYBL2, and be involved in embryonic development. 
Sequence Annotation
 ZN_FING 4 28 U1-type 1.
 ZN_FING 69 93 U1-type 2.
 MOD_RES 275 275 Phosphoserine (By similarity).  
Keyword
 Complete proteome; Cytoplasm; Metal-binding; Nucleus; Phosphoprotein; Reference proteome; Repeat; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 476 AA 
Protein Sequence
MAALTCITCR VAFRDAELQR AHYKTDWHRY NLRRKVAAMA PVTAEGFQER VRAQRAVAEA 60
AEASKGAATY CTACGKKFAT FNAYENHLGS RRHAELERKA VRAASRRVEL LNAKNLEKGL 120
GADGVDKDAV NAAIQQAIKA QPSTSPKKAP FVPTDECGRA AAGARGVPER DPTEKPPRLQ 180
WFEQQAKKLA KQQWEDGEEE GEEEEEDDED EDWEDIDSDD GLECEDPGVE DQDAEDAAAE 240
ESPPLGAIPI TDCLFCSHHS SSLVKNVAHM TKVHSFFIPD IEYLSDLKGL IKYLGEKVGV 300
GKICLWCNEK GKSFYSTEAV QAHMNDKSHC KLFTDGDAAL EFADFYDFRS SYPDYKEGQD 360
PAELEALSTD KILECDDETM ELILPSGARV GHRSLMRYYK QRFGLPRAVT VARNQKAVGR 420
VLQQYRALGW MGSTGAALMR ERDMQYVQRM KSKWMLKIGM KNNATKQMHF RAQVRF 476 
Gene Ontology
 GO:0005794; C:Golgi apparatus; IEA:Compara.
 GO:0005730; C:nucleolus; IEA:Compara.
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0008631; P:intrinsic apoptotic signaling pathway in response to oxidative stress; IEA:Compara.
 GO:0043065; P:positive regulation of apoptotic process; IEA:Compara.
 GO:0046330; P:positive regulation of JNK cascade; IEA:Compara.
 GO:0033674; P:positive regulation of kinase activity; IEA:Compara. 
Interpro
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR022755; Znf_C2H2_jaz.
 IPR003604; Znf_U1. 
Pfam
 PF12171; zf-C2H2_jaz 
SMART
 SM00355; ZnF_C2H2
 SM00451; ZnF_U1 
PROSITE
  
PRINTS