UniProt Accession

 EPMC_ECOLI; P76938; P76497 

Genbank Protein ID

 U00096; AP009048 

Genbank Nucleotide ID

 AAC75386.1; BAA16182.2 

Protein Name

 Elongation factor P hydroxylase 

Protein Synonyms/Alias

 EF-P hydroxylase; EF-P post-translational modification enzyme C 

Gene Name

 epmC 

Gene Synonyms/Alias

 yfcM; b2326; JW5381 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
28	DFNTRLIKGDDEPIY	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

 Is involved in the final hydroxylation step of the post- translational modification of translation elongation factor P (EF- P) on 'Lys-34'. Acts after beta-lysylation of 'Lys-34' by EpmA and EpmB. EpmC adds an oxygen atom to the C5 position of 'Lys-34' and does not modify the added beta-lysine. 

Sequence Annotation

  

Keyword

 Complete proteome; Monooxygenase; Oxidoreductase; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 182 AA 

Protein Sequence

Gene Ontology

 GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen; IDA:EcoCyc.
 GO:1901260; P:peptidyl-lysine hydroxylation involved in bacterial-type EF-P lysine modification; IMP:EcoCyc.
 GO:0043687; P:post-translational protein modification; IDA:UniProtKB. 

Interpro

 IPR007411; DUF462. 

Pfam

 PF04315; DUF462 

SMART

  

PROSITE

  

PRINTS